Results 101 to 110 of about 1,136,512 (313)

Blastocyst complementation-based rat-derived heart generation reveals cardiac anomaly barriers to interspecies chimera development

iScience
Summary: The use of pluripotent stem cells (PSCs) to generate functional organs via blastocyst complementation is a cutting-edge strategy in regenerative medicine.
Shunsuke Yuri, Norie Arisawa, Kohei Kitamuro, Ayako Isotani   +3 more
doaj  

The impact of molecular medicine upon early cardiovascular drug development [PDF]

, 2000
Martin W. Lunnon, Martin Braddock
openalex   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Canagliflozin attenuates post-resuscitation myocardial dysfunction in diabetic rats by inhibiting autophagy through the PI3K/Akt/mTOR pathway

iScience
Summary: This study investigated the effects of canagliflozin on myocardial dysfunction after cardiac arrest and cardiopulmonary resuscitation in diabetic rats and the underlying mechanisms.
Qihui Huang, Wei Shi, Minjie Wang, Liangliang Zhang, Yijun Zhang, Yan Hu, Sinong Pan, Bingrui Ling, Huaqing Zhu, Wenyan Xiao, Tianfeng Hua, Min Yang   +11 more
doaj  

Current Controlled Trials in Cardiovascular Medicine: a new journal for a new age (http://cvm.controlled-trials.com) [PDF]

, 2000
Curt D. Furberg, Bertram Pitt
openalex   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Cardiovascular medicine [PDF]

Journal of Vascular Surgery, 1995
openaire   +1 more source

Regenerative medicine in cardiovascular disease

Regenerative Therapy
Owing to the rapid increase in the number of people with severe heart failure, regenerative medicine is anticipated to play a role in overcoming the limitations inherent in existing surgical interventions. There are essentially two types of cardiac regenerative therapies for a failing heart.
Takasumi Goto, Yuki Nakamura, Yoshito Ito, Shigeru Miyagawa   +3 more
openaire   +3 more sources

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Editorial: Frontiers in Cardiovascular Medicine: Rising Stars 2021

Frontiers in Cardiovascular Medicine, 2022
Lijun Wang, Lijun Wang, Gui-e Xu, Gui-e Xu, Longlu Pan, Elena Aikawa, Masanori Aikawa, Junjie Xiao, Junjie Xiao, Ngan F. Huang, Ngan F. Huang   +10 more
doaj   +1 more source