Results 51 to 60 of about 1,109,815 (338)

Emerging roles of the RNA modifications N6-methyladenosine and adenosine-to-inosine in cardiovascular diseases

Molecular Therapy: Nucleic Acids, 2022
Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with key events of cardiovascular diseases and metabolic disorders.
Vilbert Sikorski, Antti Vento, Esko Kankuri   +2 more
doaj  

Changes in Continuous, Long-Term Heart Rate Variability and Individualized Physiological Responses to Wellness and Vacation Interventions Using a Wearable Sensor

Frontiers in Cardiovascular Medicine, 2020
There are many approaches to maintaining wellness, including taking a simple vacation to attending highly structured wellness retreats, which typically regulate the attendee's personal time and activities.
Abhishek Pratap, Abhishek Pratap, Steve Steinhubl, Elias Chaibub Neto, Stephan W. Wegerich, Christine Tara Peterson, Lizzy Weiss, Sheila Patel, Sheila Patel, Deepak Chopra, Deepak Chopra, Paul J. Mills   +11 more
doaj   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Arterial Blood Pressure Feature Estimation Using Photoplethysmography [PDF]

Armin Soltan Zadi, Raichel Alex, Rong Zhang, Donald E. Watenpaugh, Khosrow Behbehani, "Arterial Blood Pressure Feature Estimation Using Photoplethysmography",Computers in Biology and Medicine,Volume 102, 1 November 2018, Pages 104-111, 2018
Continuous and noninvasive monitoring of blood pressure has numerous clinical and fitness applications. Current methods of continuous measurement of blood pressure are either invasive and/or require expensive equipment. Therefore, we investigated a new method for the continuous estimation of two main features of blood pressure waveform: systolic and ...
arxiv   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Predicting stroke and myocardial infarction risk in Takayasu arteritis with automated machine learning models

iScience, 2023
Summary: Few models exist for predicting severe ischemic complications (SIC) in patients with Takayasu arteritis (TA). We conducted a retrospective analysis of 703 patients with TA from January 2010 to December 2019 to establish an SIC prediction model ...
Yi-Ting Lu, Zeng-Lei Zhang, Xing-Yu Zhou, Di Zhang, Tao Tian, Peng Fan, Ying Zhang, Xian-Liang Zhou   +7 more
doaj  

Joint segmentation and classification of retinal arteries/veins from fundus images [PDF]

Artificial Intelligence in Medicine, Volume 94, 2019, Pages 96-109, ISSN 0933-3657, 2019
Objective Automatic artery/vein (A/V) segmentation from fundus images is required to track blood vessel changes occurring with many pathologies including retinopathy and cardiovascular pathologies. One of the clinical measures that quantifies vessel changes is the arterio-venous ratio (AVR) which represents the ratio between artery and vein diameters ...
arxiv   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Histo-blood group glycans in the context of personalized medicine [PDF]

Biochimica et Biophysica Acta 1860 (2016) 1596-1607, 2019
Background: A subset of histo-blood group antigens including ABO and Lewis are oligosaccharide structures which may be conjugated to lipids or proteins. They are known to be important recognition motifs not only in the context of blood transfusions, but also in infection and cancer development.
arxiv   +1 more source

Integrative genomics in cardiovascular medicine [PDF]

Cardiovascular Research, 2012
Integrative genomics studies have greatly advanced our understanding of cardiovascular pathophysiology over the last decade. Here, we highlight the strengths and challenges of this cutting-edge approach and provide examples where novel insights have arisen through the integration of multi-level genomic information and cardiac physiology. Going forward,
Ware, JS, Petretto, E, Cook, SA
openaire   +5 more sources