The association of triglyceride-glucose index and related indices with all-cause and cardiovascular mortality in biologically aging populations. [PDF]
Cheng MQ +5 more
europepmc +1 more source
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
High salt intake and its dual impact on obesity and cardiovascular mortality in individuals over 50: a paradoxical relationship. [PDF]
Luo Y +9 more
europepmc +1 more source
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti +13 more
wiley +1 more source
Effects of Eicosapentaenoic Acid vs Eicosapentaenoic/Docosahexaenoic Acids on Cardiovascular Mortality: Meta-Analysis of Clinical Trials. [PDF]
Sheppard JP +8 more
europepmc +1 more source
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Dietary cholesterol intake and egg consumption in relation to all-cause and cardiovascular mortality after stroke. [PDF]
Xia L, Xu T, Zhan Z.
europepmc +1 more source
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Tali Eviatar +35 more
wiley +1 more source
Integrated risks from air pollution and climate extremes: synergistic effects of ozone, heat, and humidity on cardiovascular mortality. [PDF]
Wei Q +11 more
europepmc +1 more source

