Results 241 to 250 of about 291,532 (299)

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Single‐cell sequencing reveals the role of IL‐33+ endothelial subsets in promoting early gastric cancer progression

open access: yesiMeta, EarlyView.
A single‐cell atlas was established to reveal the molecular characteristics of early gastric cancer (EGC). In combination with organoids, animal models, and clinical samples, it was found that subpopulations such as pit mucous‐like cell (PMC‐like), proliferating cell (PC), CH25H+ CD4+ T cell, IL‐33+ endothelial cell, and ADAMTSL2+ endothelial cell are ...
Li Zhou   +15 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

open access: yesInterdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li   +9 more
wiley   +1 more source

Integrating surface‐enhanced Raman scattering with machine learning: Pioneering a comprehensive diagnostic and therapeutic platform for cancer management

open access: yesInterdisciplinary Medicine, EarlyView.
Integrating Surface‐Enhanced Raman Scattering (SERS) with machine learning creates a powerful platform for cancer management. This approach enhances diagnostic precision through non‐invasive molecular fingerprinting and enables real‐time therapeutic monitoring. By combining SERS with machine learning, it offers a comprehensive solution for early cancer
Heng‐Zhou He   +9 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

open access: yesInterdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao   +6 more
wiley   +1 more source

Accuracy and reproducibility of ChatGPT responses to real‐world drug information questions

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction The expanding use of Chat Generative Pre‐Trained Transformer (ChatGPT, OpenAI, San Francisco, CA) for drug information may enhance access to information. However, it is crucial to assess the accuracy and reproducibility of ChatGPT responses to drug information questions, examining its utility and limitations in clinical decision ...
Shikha Khatri   +3 more
wiley   +1 more source

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