Fluid-structure interaction simulation of pulse propagation in arteries : numerical pitfalls and hemodynamic impact of a local stiffening [PDF]
, 2014 When simulating the propagation of a pressure pulse in arteries, the discretization parameters (i.e. the time step size and the grid size) need to be chosen carefully in order to avoid a decrease in amplitude of the traveling wave due to numerical ...
Degroote, Joris +4 more
core +1 more source
An anatomically detailed arterial-venous network model. Cerebral and coronary circulation
Frontiers in Physiology, 2023 In recent years, several works have addressed the problem of modeling blood flow phenomena in veins, as a response to increasing interest in modeling pathological conditions occurring in the venous network and their connection with the rest of the ...
Lucas O. Müller +7 more
doaj +1 more source
Cardiovascular deconditioning during long-term spaceflight through multiscale modeling [PDF]
npj Microgravity 6(1), 27, 2020, 2020 Human spaceflight has been fascinating man for centuries, representing the intangible need to explore the unknown, challenge new frontiers, advance technology and push scientific boundaries further. A key area of importance is cardiovascular deconditioning, that is, the collection of hemodynamic changes - from blood volume shift and reduction to ...
arxiv +1 more source
Using skewness and the first-digit phenomenon to identify dynamical transitions in cardiac models [PDF]
, 2016 Disruptions in the normal rhythmic functioning of the heart, termed as arrhythmia, often result from qualitative changes in the excitation dynamics of the organ.
Easwaran, Soumya +3 more
core +2 more sources
Patient-Specific Cardiovascular Computational Modeling: Diversity of Personalization and Challenges
Journal of Cardiovascular Translational Research, 2018 Patient-specific computer models have been developed representing a variety of aspects of the cardiovascular system spanning the disciplines of electrophysiology, electromechanics, solid mechanics, and fluid dynamics.
R. Gray, P. Pathmanathan
semanticscholar +1 more source
Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development.
Applied In Vitro Toxicology, 2016 Cardiovascular diseases are prevalent worldwide and are the most frequent causes of death in the United States. Although spending in drug discovery/development has increased, the amount of drug approvals has seen a progressive decline.
João Ribas +7 more
semanticscholar +1 more source
Diverse routes to oscillation death in a coupled-oscillator system. [PDF]
, 2009 We study oscillation death (OD) in a well-known coupled-oscillator system that has been used to model cardiovascular phenomena. We derive exact analytic conditions that allow the prediction of OD through the two known bifurcation routes, in the same ...
A. Stefanovska +8 more
core +2 more sources
Respiratory Sinus Arrhythmia Mechanisms in Young Obese Subjects [PDF]
, 2020 Autonomic nervous system (ANS) activity and imbalance between its sympathetic and parasympathetic components are important factors contributing to the initiation and progression of many cardiovascular disorders related to obesity.
Busacca, Alessandro +10 more
core +1 more source
The role of mathematical modeling in VOC analysis using isoprene as a prototypic example [PDF]
J. Breath Res. 5 (2011) 037102, 2011 Isoprene is one of the most abundant endogenous volatile organic compounds (VOCs) contained in human breath and is considered to be a potentially useful biomarker for diagnostic and monitoring purposes. However, neither the exact biochemical origin of isoprene nor its physiological role are understood in sufficient depth, thus hindering the validation ...
arxiv +1 more source
Oxidative Medicine and Cellular Longevity, 2017 Oxidative states exert a significant influence on a wide range of biological and molecular processes and functions. When their balance is shifted towards enhanced amounts of free radicals, pathological phenomena can occur, as the generation of reactive ...
F. Angelini +13 more
semanticscholar +1 more source