Results 271 to 280 of about 8,503,937 (347)

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song   +37 more
wiley   +1 more source

Electronic Cigarettes and Cardiovascular Risk: Science, Policy and the Cost of Certainty

open access: yesEuropean Cardiology Review, 2019
Olusola A Orimoloye   +4 more
doaj   +1 more source

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

open access: yesAdvanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei   +8 more
wiley   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy