Results 161 to 170 of about 2,745,145 (306)

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Risk Factor, Mortality and Infection Rate of Mediastinum After Delayed Sternal Closure in Congenital Heart Surgery Patients

, 2001
Background: Congenital heart surgery may lead to myocardial swelling and hemodynamic instability. Delayed sternal closure may be beneficial in this setting.
박한기, 박영환
core  

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Clinical application and management of temporary mechanical circulatory support: A clinical consensus

Chinese Medical Journal
Nianguo Dong, Liangwan Chen, Xin Chen, Huishan Wang, Yingbin Xiao, Xianqiang Wang, Jinsong Huang, Yang Yan, Pramod Bonde, Neel Sodha, Pavan Atluri, Juan Pablo Maureira, André Vincentelli, Masanobu Yanase, Yixuan Wang, Haitao Zhang, Xiaotong Hou, Yoshijuki Takami, Pascal Leprince, Thierry Folliguet, Frank W Sellke, Chinese Society for Thoracic and Cardiovascular Surgery; Chinese Association of Cardiovascular Surgeons; Cardiac Critical Care Professional Committee of Chinese Medical Association; Chinese Society of Extracorporeal Life Support; European Society of Cardiovascular and Endovascular Surgery; French Society of Thoracic and Cardiovascular Surgery; Japanese Society for Cardiovascular Surgery; Japanese Society of Artificial Organs, Sihan Zhou, Xiuyuan Hao   +23 more
doaj   +1 more source

Beyond Thirty Days: Risk, Reintervention, and Recovery in Contemporary Cardiovascular Surgery. [PDF]

J Cardiovasc Dev Dis
Androutsopoulou V, Zotos PA, Magouliotis DE.   +2 more
europepmc   +1 more source

First Experience of Thoracic Surgery with the da VinciTM Surgical System in Korea

, 2006
Video-assisted thoracoscopic surgery has gained a broad acceptance for various thoracic lesions because it is the minimally invasive surgery with little tissue trauma, less pain, improved cosmetic results and short recovery time.
박인규, 김대준, 정경영
core  

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

Advanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu, Jingzhe Wang, Xu Chen, Yuntong Yang, Ping Wei, Han Xie, Honghao Wang, Chunyu Zhang, Siyi Xu, Qi Wang, Chunlong Zhong, Jing Zhang   +11 more
wiley   +1 more source

The Leadership of the Brazilian Journal of Cardiovascular Surgery in the Digital Transformation of Cardiovascular Surgery. [PDF]

Braz J Cardiovasc Surg
Jonke VM, Murad H, Luppi A.
europepmc   +1 more source

Dementia and Cardiovascular Surgery

Circulation Journal, 2018
openaire   +3 more sources