Results 201 to 210 of about 2,734,487 (306)

Interventions for Silent Brain Infarction and Perioperative Neurocognitive Disorders in Cardiovascular Surgery (INSPIRE): study protocol for a multicentre randomised controlled trial. [PDF]

BMJ Open
Wang L, Li S, Devereaux PJ, Lv H, Li T, Zhang L, An Y, Chen J, Wei C, Zhao L, Peng Y, Shi J.   +11 more
europepmc   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Simultaneous bispectral index and near-infrared spectroscopy monitoring to evaluate two induction protocols in elective cardiovascular surgery. [PDF]

J Cardiothorac Surg
Eke H, Toprak B, Bozkurt ED.
europepmc   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Influence of Frailty Syndrome on Outcomes of Cardiovascular Surgery in Elderly Patients. [PDF]

Braz J Cardiovasc Surg
Salles FB, Fighera GZ, Costa VB, Khalil KH, Kalil RAK, Eibel B.   +5 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Acute kidney injury secondary to overtreatment of hypertension in an elderly patient undergoing combined cardiovascular surgery: A case report. [PDF]

Med Int (Lond)
Paydas S, Sezgin AT.
europepmc   +1 more source

Intraoperative Indocyanine Green Near-Infrared Angiography for Redo Valve Replacement

The Thoracic & Cardiovascular Surgeon Reports
Brian Solomon, Andreas Sarantopoulos, Thomas Caranasos   +2 more
doaj   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Takotsubo cardiomyopathy in an infant with acute mediastinitis following cardiovascular surgery: An unusual diagnosis and successful management. [PDF]

Ann Pediatr Cardiol
Rubio-Duarte AF, Diaz-Caraballo MA, Ramirez-Jaramillo V, Castro-Monsalve JM.   +3 more
europepmc   +1 more source