Results 161 to 170 of about 555,957 (260)

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

Advanced Science, EarlyView.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang, Jintian Yu, Liang Yuan, Ziliang Fu, Yiming Yao, Lingna Chen, Shixiong Chen, Aikemu Ainiwaer, Xiaolin Cui   +8 more
wiley   +1 more source

Evaluation of patient involvement in patient safety in cardiovascular surgery intensive care units: a qualitative study. [PDF]

BMC Cardiovasc Disord
Güner Y, Üçüncüoğlu M, Yürük MA.
europepmc   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial.

JAMA Netw Open
Pan T, Xu C, Wang YP, Wang HL, Su WX, Zhang HT, Zhu EJ, Li YT, Lv ZK, Zhu TT, Xu ZW, Gao Y, Xu CZ, Shi J, Ji WJ, Duan ZH, Zhang C, Xu ZJ, Li KS, Chong H, Zhu XY, Xue YX, Xu WZ, Chen C, Zhao WW, Ye JX, Ge M, Xu GJ, Wu SM, Pan J, Wang DJ, Qu JZ, Wang Q.   +32 more
europepmc   +1 more source

Neither tranexamic acid nor ulinastatin affects the activated clotting time values in healthy volunteers and heparinized cardiovascular surgery patients. [PDF]

J Cardiothorac Surg
Jia B, Deng J, Yao Y, Evidence in Cardiovascular Anesthesia Group.   +3 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Preoperative visceral fat and muscle loss after cardiovascular surgery: A retrospective cohort study. [PDF]

JPEN J Parenter Enteral Nutr
Shimizu K, Matsuzawa R, Nakamura S, Miyoshi H, Murakawa K, Kawakami H, Mineo R, Gotake Y, Ohnaka M, Matsumori M, Tamaki A.   +10 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Preoperative frontal EEG power spectral features associated with psychomotor subtypes of postoperative delirium in cardiovascular surgery: a prospective study. [PDF]

Sci Rep
Nagata C, Hata M, Miyazaki Y, Miyoshi R, Futamura M, Wada T, Yoshida K, Miyagawa S, Ikeda M, Ueno T.   +9 more
europepmc   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source