Results 161 to 170 of about 273,684 (247)

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source

Intravenous esketamine as a detumescence agent for intraoperative penile erection during urological surgeries: a retrospective clinical analysis. [PDF]

BMC Anesthesiol
Yao W, Shi R, Zhang L, Wang J, Chen Z.
europepmc   +1 more source

Wearable Hyperspectral Photoplethysmography Allows Continuous Monitoring of Exercise‐Induced Hypertension

Advanced Science, EarlyView.
A wearable hyperspectral photoplethysmography (HS‐PPG) is reported for continuous blood pressure (BP) monitoring. The HS‐PPG module integrates an ultrathin double‐folded solid immersion grating microspectrometer (DFSIG‐µSPEC), achieving a high spectral resolution of 3.4 nm.
Jung‐Woo Park, Jaehyeok Park, Jaehun Jeon, Seongok Chae, Gi Beom Kim, Geonhui Han, Hyung‐Soon Park, Yong Jeong, Ki‐Hun Jeong   +8 more
wiley   +1 more source

Surgical outcomes for necrotizing enterocolitis in Dutch infants born before 26 weeks' gestation. [PDF]

BJS Open
van Varsseveld OC, Pijpers AGH, Imren C, Derikx JPM, van den Akker CHP, van Schuppen J, Keyzer-Dekker CMG, Vermeulen MJ, Schurink M, Lindeboom MYA, Kooi EMW, Hulscher JBF.   +11 more
europepmc   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

The Optimal Age for Oophorectomy in Women with Benign Conditions: A Narrative Review. [PDF]

J Pers Med
Giannakaki AG, Giannakaki MN, Nikolettos K, Pagkaki C, Tsikouras P.   +4 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

Vasoactive-inotropic agents in pediatric patients undergoing cardiac surgery: A single-center retrospective study. [PDF]

Medicine (Baltimore)
Sun YT, Wang LH, Yao YT, Evidence in Cardiovascular Anesthesia (EICA) Group.   +3 more
europepmc   +1 more source

SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway

Advanced Science, EarlyView.
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang, Siyuan Qin, Xiaokang Li, Ming Chang, Tianzi Wei, Xin Huang, Haibo Tong, Xia Guo, Yi Lu, Jian Zhang   +9 more
wiley   +1 more source

Transfemoral Transseptal Mitral Valve-in-Valve-in-Valve of a Degenerated Transcatheter in Surgical Bioprosthesis. [PDF]

JACC Case Rep
Crociani MF, Di Mario C, Stolcova M, Ciardetti N, Mattesini A, Maiani S, Nardi G, Di Muro FM, Mandarano R, Meucci F.   +9 more
europepmc   +1 more source