Results 201 to 210 of about 321,461 (316)

Metabolic and nutritional status changes after 10% weight loss in severely obese patients treated with laparoscopic surgery vs integrated medical treatment [PDF]

, 2007
Alfonsi L, CONTALDO, FRANCO, del Genio A, del Genio F, del Genio G, FINELLI, CARMINE, MARRA, MAURIZIO, PASANISI, FABRIZIO, Rossetti G   +8 more
core   +1 more source

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source

Adherence to Surgical Antimicrobial Prophylaxis Guidelines and Improvement Efforts: A Single-Center, Pre- and Post-Intervention Comparison Study. [PDF]

Health Sci Rep
Yamamoto C, Nukui Y, Kosaka T, Aoto K, Kozen R, Hasegawa K, Ota C, Inoue Y, Taniguchi M, Hamashima R, Furukawa K, Kikuchi K, Nakanishi A, Teramukai S, Horii Y, Sawa T.   +15 more
europepmc   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Comparable lipid profile improvements after sleeve gastrectomy and Roux-en-Y gastric bypass: findings from a single center retrospective cohort. [PDF]

BMC Surg
Tasdelen İ, Ergin A, Yaz AS, Bilgin Mİ, Gunes Y, Fersahoğlu MM, Bulut NE.   +6 more
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Western University Protocol for Obstructive Sleep Apnea. [PDF]

J Clin Med
Simsim R, Rotenberg B.
europepmc   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry. [PDF]

JACC Adv
Erzingatzian A, Al-Baldawi Z, Ruel I, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Paquette M, Baass A, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Brunham LR, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Ransom T, McPherson R, Piazza N, de Varennes B, Genest J, Iatan I.   +27 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source