Results 41 to 50 of about 202,465 (263)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Adjuvant Pericardial Sac Restraining in Heart Failure Treatment. A Medical Hypothesis Illustrated by a Case Report

Brazilian Journal of Cardiovascular Surgery, 2016
Ventricular constraint therapy has been used to prevent and reverse the progression of heart failure in ischemic and nonischemic cardiomyopathies. We hypothesized that ventricular restraint should be tried by closing the pericardium that was previously ...
Paulo Roberto Barbosa Evora, Minna Moreira D. Romano, Luis Gustavo Gali, André Schmidt, Alfredo José Rodrigues   +4 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Post-surgical infection in elective cardiac surgeries: what is the role of dental evaluation? A retrospective study [PDF]

Einstein (São Paulo)
Objective: To evaluate the prevalence and clinical characteristics of post-surgical infections after coronary and/or valvular heart surgery at a tertiary hospital and to examine the relationship between these infections and prior dental evaluation ...
Ana Eliza Durães de Faria, Itamara Lúcia Itagiba Neves, Ricardo Simões Neves, Samara Caroline Fernandes Galvani, Henrique Furukawa, Bianca de Fatima Borim Pulino, Heloisa Fonseca Marão, Raphael Capelli Guerra, Marcela Alves dos Santos-Paul   +8 more
doaj   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

La calidad de vida de los pacientes después de una cirugía cardiaca en un hospital de Colombia

Cirugía Cardiovascular
Resumen: Objetivos: Conocer tanto la calidad de vida de los pacientes sometidos a una intervención cardiaca como los núcleos del EQ-5D-5L más afectados, y determinar qué factores clínicos se asocian a una mala calidad de vida.
Jhon Alexander Barrero, Fernando Andrés Rada, Catalina Vásquez Casas, Diana Marcela Franco, Juan David Diaz, Kelly Maileth Murgas, Laura Melisa Pulido, Angie Michell Garzón, Laura Victoria Briñez, Gilma Hernandez, Jaime Camacho Mackenzie   +10 more
doaj   +1 more source

Association of hematological and biochemical tests and complications after cardiovascular surgery

O Mundo da Saúde, 2022
Cardiac surgery has postoperative complications of varying severities. Knowing the predictors of such complications can minimize risks and increase patient survival.
Sandra Leontina Graube, Karen Rafaela Okaseski, Bruna Felipin Ludvig, Silvana Agnolleto Bewanger, Vivian Lemes Lobo Bittencourt, Christiane de Fátima Colet, Eliane Roseli Winkelmann   +6 more
doaj  

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Inflammation and Perioperative Cardiovascular Events

Cells
Surgery and anesthesia induce a stress response that provokes increased sympathetic stimulation, secretion of cortisol, hypercoagulability, and systemic inflammatory response.
Peter Poredos, Radko Komadina
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source