Results 91 to 100 of about 2,134,150 (323)

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice

, 2023
Shing‐Hsien Chou, Hung-Chen Lin, Shao-Wei Chen, Yu-Ting Tai, Shih‐Ming Jung, Fu‐Hsiang Ko, Jong‐Hwei S. Pang, Pao‐Hsien Chu   +7 more
openalex   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Computational simulations of coronary artery bifurcation stenting using realistic plaque distribution and materials

Scientific Reports
Coronary bifurcation stenting is a technically demanding procedure that benefits from precise preoperative planning. Finite element analysis (FEA) offers a powerful framework for simulating stent deployment, with full-plaque (FP) models representing the ...
Wei Wu, Shijia Zhao, Rakshita Ramesh Bhat, Yash Vardhan Trivedi, Parth Munjal, Rahul Chikatimalla, Ruben K.A. Tapia-Orihuela, Hammad Zafar, Haritha Darapaneni, Komal Arora, Changkye Lee, Yiannis S. Chatzizisis   +11 more
doaj   +1 more source

Healthcare systems data in the context of clinical trials – A comparison of cardiovascular data from a clinical trial dataset with routinely collected data

, 2023
Archie Macnair, Matthew Nankivell, Macey L. Murray, Stuart D. Rosen, S.E. Appleyard, Matthew R. Sydes, Sylvia Forcat, Andrew Welland, Noel W. Clarke, Stephen Mangar, Howard Kynaston, Roger Kockelbergh, Abdulla Al-Hasso, John Deighan, John C. Marshall, Mahesh Parmar, Ruth E. Langley, Duncan C. Gilbert   +17 more
openalex   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Balloon protection of the mesenteric-renal vessels during embolectomy of acute paravisceral aortic occlusion

Journal of Vascular Surgery Cases and Innovative Techniques
Acute thrombosis of the aorta is an uncommon, but potentially devastating, vascular emergency. The absence of pathognomonic signs or symptoms makes the diagnosis challenging and, often, time consuming.
May Dvir, MS, Carmelina Gurrieri, MD, Andrew D. Calvin, MD, MPH, Thomas Carmody, MD, Tiziano Tallarita, MD   +4 more
doaj   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Analysis of changes in leg volume parameters, and orthostatic tolerance in response to lower body negative pressure during 59 days exposure to zero gravity Skylab 3 [PDF]

The cardiovascular responses of the Apollo crewmen associated with postflight evaluations indicate varying decrements of orthostatic tolerance. The postflight changes indicate a slightly diminished ability to the cardiovascular system to function ...
Barnett, R. D., Carroll, D. R., Gowen, R. J.   +2 more
core   +1 more source