Results 41 to 50 of about 25,370 (217)

In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence

Clinical Pharmacology &Therapeutics, EarlyView.
Conventional clinical trials remain the benchmark for evaluating therapeutic safety and efficacy, yet they are constrained by escalating costs, withdrawal over the extended follow‐up periods, recruitment difficulties, ethical limits, and a restricted ability to characterize heterogeneous populations.
Maximilian Balmus, Sheng‐Ya Wang, Edward W. G. Ashton, Rosie K. Barrows, Molly Monks, Yuzhang Ge, Arthur Lefebvre, Steven A. Niederer   +7 more
wiley   +1 more source

Safety evaluation of electrical cardioversion in the presence left ventricular thrombus

Journal of Stroke and Cerebrovascular Diseases
Background: Electrical cardioversion is an effective and safe procedure for most patients. While left atrial thrombus is an absolute contraindication for an elective cardioversion, there is limited data on cardioversion in patients with left ventricular ...
M Marwan Dabbagh, MD, Saqer Alkharabsheh, MD, Mohamed Khayata, MD, Patrick Collier, MD   +3 more
doaj   +1 more source

Impact of electric cardioversion on platelet activation.

PLoS ONE, 2021
IntroductionAtrial fibrillation (AF) comes along with high risk of stroke. This risk continues even after re-establishing sinus rhythm with cardioversion.
Harald Haidl, Johanna Gaugler, Gerhard Cvirn, Hildegard Jasser-Nitsche, Wolfgang Schwinger, Sina Pohl, Egbert Bisping, Siegfried Gallistl, Axel Schlagenhauf   +8 more
doaj   +1 more source

Anaesthesia for cardioversion [PDF]

Anaesthesia, 1996
Summary Cardioversion is a minor procedure requiring sedation and analgesia. However, it is often performed out‐of‐hours in remote sites by inexperienced anaesthetists. An understanding is required both of the pathophysiology underlying cardiac arrhythmias and of the technical side of defibrillation equipment, including electrical ...
openaire   +4 more sources

Flow chart of the cardioversion.

, 2018
This figure shows our study design and the results of the cardioversion. PeAF: persistent atrial fibrillation, TEE: transesophageal echocardiography, LAA: left atrial appendage, SEC: spontaneous echo contrast, DCCV: direct current cardioversion, SR ...
In-Cheol Kim (6061502), Jongmin Hwang (3992909), Seung-Woon Jun (6061496), Seongwook Han (6061508), Cheol Hyun Lee (5958890), Hyuck-Jun Yoon (3402902), Chang-Wook Nam (3402923), Hyungseop Kim (6061505), Yun-Kyeong Cho (3402941), Sang-Woong Choi (6061499), Hyoung-Seob Park (6061493), Seung-Ho Hur (736905), Sang Hoon Lee (211083)   +12 more
core   +1 more source

A Comparison of Safety and Outcome Using Three Different Sedation Strategies During Pulsed Field Ablation for Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging modality for atrial fibrillation (AF) ablation. However, adequate sedation of patients during treatment is imperative. Objective Our aim was to compare safety and outcome after deep sedation (DS) managed by electrophysiology staff (EP‐DS), DS by an anaesthesia nurse (AN‐DS), and general ...
Christina Alhede, Laurits Juhl Heinsen, Mille Ravn Sandgaard, Jacob Pontoppidan, Katrine Væsel Wade, Uffe Gang, Steen Buus Kristiansen, Arne Johannessen, Armin Osmanagic, Camilla Lundegaard Asferg, Peter Steen Hansen, Sam Riahi, Martin H. Ruwald, Peter Karl Jacobsen, Niels C. F. Sandgaard   +14 more
wiley   +1 more source

Perceived Social Support in Atrial Fibrillation Care: Implications for Nurse‐Led Education and Follow‐Up

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To describe the level, content and sources of perceived social support among adults with atrial fibrillation, and to identify clinical, lifestyle and care pathway factors associated with perceived support. Design A cross‐sectional survey design.
Outi Kähkönen, Niina Raitanen, Juha Hartikainen, Anna‐Mari Hekkala, Signe Stelling Risom, Tone M. Norekvål, Ying Lau, Ville Hautamäki, Anneli Vauhkonen   +8 more
wiley   +1 more source

Rising Comorbidity Burden in Inpatient Atrial Fibrillation Catheter Ablation: Temporal Trends and In‐Hospital Outcomes

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Despite advancements in catheter ablation (CA) technique and expertise, success rates of atrial fibrillation (AF) ablation have not substantially improved in recent years. Treating patients with advanced age and higher comorbidities may limit success rates while increasing complications.
Eran Leshem, Bar Ehrenberg, Adam Folman, Mark Kazatsker, Ariel Roguin, Gilad Margolis   +5 more
wiley   +1 more source

Management of Left Atrial Appendage Thrombi and Spontaneous Echo Contrast

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background To analyze the efficacy and safety of various anticoagulation strategies/regimen used for managing thrombus or spontaneous echo contrast in the left atrial appendage. Methods Thrombus or spontaneous echo contrast in the left atrial appendage was detected via transesophageal echocardiography in 83 patients, most often during a stroke
Timnou Bekouti Jean, Ravakiniaina Ranaivosoa Mialy, Ateba Ateba Nelly Stella, Tsague Kegni Hermann, Rambolarimanana Mansh, Ndobo Julia Valérie, Imbey Eheth Levy, Maury Philippe, Diawara Alpha, Roynard Jean Louis, Boombhi Jerome Hilaire   +10 more
wiley   +1 more source

ST-segment elevation with elective DC cardioversion.

, 1981
Elective direct-current cardioversion was performed in three patients with atrial fibrillation. Transient ST-segment elevation on monitored leads, lasting seconds, was recorded after cardioversion in all three patients.
P K Chun, J E Davia, D J Donohue
core   +1 more source