Results 91 to 100 of about 9,640,693 (303)
, 2011 "As required by Connecticut General Statutes (C.G.S.) section 19a-634 this report is one of three components of the Department of Public (DPH) Health Office of Health Care Access' (OHCA) approach to planning for Connecticut's health care system"--P. 4.; "
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An act concerning improvement of cardiac care
, 2007 Title from cover.; "Public Act 05-167, An Act Concerning the Improvement of Cardiac Care ..."--p.
Connecticut. Cardiac Care Data Committee.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Quality of Case Reports and Adherence to the CARE (Case Report) Guidelines: Protocol for a Scoping Review [PDF]
Journal of Advanced Biomedical SciencesBackground & Objectives: The use of reporting guidelines aims to enhance the completeness and transparency of biomedical publications. The CARE guideline was developed in 2013 to assist researchers in improving the reporting of their case reports.
Abolfazl Taheri +5 more
doaj
Description based on: Issue 12 (Nov./Dec. 1996); title from caption.Not distributed to depository libraries in a physical form, Issue 23, 2000-Previously classed: HE 23.1017:Mode of access: Internet.Published by the National Child Care Information Center
United States. Child Care Bureau. +1 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source