Results 121 to 130 of about 7,992,081 (314)

Passages to inclusion : creating systems of care for all children : monograph for state, territorial and tribal child care administrators.

open access: yes, 1997
Shipping list no.: 97-0230-P."This monograph was prepared by the National Child Care Information Center (NCCIC) as part of the Child Care Technical Assistance Project, a project of the Child Care Bureau, Administration for Children and Families ...
United States. Child Care Bureau.   +1 more
core  

What causes patients to trust medical professionals? Insights from mothers in Juba

open access: yesSouth Sudan Medical Journal, 2017
Trust in medical professionals is an important aspect of demand for health care in South Sudan, without which many patients may never attempt to access clinics and hospitals.
Rachel Ayrton   +2 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Other title: Long Term Care

open access: yes
application/pdfA set of 5 documents provided by the Office of the Kansas Long Term Care Ombudsman, with resources and information on Long Term Care.Kansas Office of the State Long-Term Care Ombudsman -- Kansas Office of the State Long-Term Care Ombudsman
Kansas. Long Term Care Ombudsman.
core  

To care or not to care

open access: yes, 2005
In the nursing profession, caring is the most essential part. It is used by nurses’ everyday and is an integral part in the responsive nurse-patient relationship. The main aim of this study was to investigate caring in nursing. Furthermore, because of Maslach (1998) statement that close contact within the nurse-patient relationship contributes to ...
Jahn, Sandra, Wedebrand, Sandra
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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