Results 111 to 120 of about 1,077,642 (353)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Landscape of Medication Management in the Minnesota Patient-Centered Medical Home (PCMH) [PDF]
INNOVATIONS in Pharmacy, 2013 Purpose: To describe the landscape of medication management within the patient-centered medical homes (PCMH) in the state of Minnesota. Methods: An electronic survey of care coordinators within PCMHs certified with the Department of Health in state of ...
Donald L. Uden, PharmD, FCCP +3 more
doaj
Frontiers in Oncology, 2015 IntroductionThis study aimed to assess psychological distress (PD) as scored by the Distress Thermometer (DT) in adult primary brain tumor (PBT) patients and caregivers in a clinic setting, and ascertain if any high risk sub-groups for PD exist. Material
Wafa eTrad +13 more
doaj +1 more source
California Youth Transitions to Adulthood Study (CalYOUTH): Early Findings from the Child Welfare Worker Survey [PDF]
, 2015 This report presents findings from the Child Welfare Worker Survey, an on-line survey of 235 California child welfare workers and their perceptions of key characteristics of the service delivery context of extended foster care, including: the ...
Katherine Halsted +3 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
International Journal of Integrated Care, 2019 Introduction: Over a third of Australian children have long-term health conditions, often involving multiple organ systems and resulting in complex health care needs.
Yvonne Zurynski +4 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The impact of central government steering and local network dynamics on the performance of mandated service delivery networks: the case of the Primary Health Care networks in Flanders [PDF]
, 2013 This paper focuses on the impact of central – local relations on the performance of local service delivery networks set up by central government. Analyzing network literature leaves us with some questions about the impact of coordination strategies of ...
De Rynck, Filip +2 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source