Results 61 to 70 of about 306,765 (262)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluating an Enterprise-Wide Initiative to enhance healthcare coordination for rural women Veterans using the RE-AIM framework

Frontiers in Health Services
IntroductionThe Veterans Health Administration (VA) Office of Rural Health (ORH) and Office of Women's Health Services (OWH) in FY21 launched a three-year Enterprise-Wide Initiative (EWI) to expand access to preventive care for rural, women Veterans ...
Mark R. Relyea, Mark R. Relyea, Rebecca L. Kinney, Rebecca L. Kinney, Eric C. DeRycke, Sally Haskell, Sally Haskell, Kristin M. Mattocks, Kristin M. Mattocks, Lori A. Bastian, Lori A. Bastian   +10 more
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Landscape of Medication Management in the Minnesota Patient-Centered Medical Home (PCMH) [PDF]

INNOVATIONS in Pharmacy, 2013
Purpose: To describe the landscape of medication management within the patient-centered medical homes (PCMH) in the state of Minnesota. Methods: An electronic survey of care coordinators within PCMHs certified with the Department of Health in state of ...
Donald L. Uden, PharmD, FCCP, Jody L. Lounsbery, PharmD, BCPS, Jean Moon, PharmD, BCACP, Margaret L. Wallace, PharmD, BCACP   +3 more
doaj  

Screening for psychological distress in adult primary brain tumor patients and caregivers: considerations for cancer care coordination

Frontiers in Oncology, 2015
IntroductionThis study aimed to assess psychological distress (PD) as scored by the Distress Thermometer (DT) in adult primary brain tumor (PBT) patients and caregivers in a clinic setting, and ascertain if any high risk sub-groups for PD exist. Material
Wafa eTrad, Eng-Siew eKoh, Eng-Siew eKoh, Maysaa eDaher, Maysaa eDaher, Alanah eBailey, Marina eKastelan, Marina eKastelan, Dianne Maree Legge, Marcia eFleet, Grahame Kenneth Simpson, Grahame Kenneth Simpson, Elizabeth Jane Hovey, Elizabeth Jane Hovey   +13 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Care coordination for children with medical complexity results in savings for the healthcare system and for families

International Journal of Integrated Care, 2019
Introduction: Over a third of Australian children have long-term health conditions, often involving multiple organ systems and resulting in complex health care needs.
Yvonne Zurynski, Christie Breen, Lisa Altman, Susan Woolfenden, Joanne Ging   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Coordinating community care [PDF]

BMJ, 1988
S G, Barber, P W, Haynes
openaire   +2 more sources