Results 51 to 60 of about 4,448,722 (291)

Effective health care for older people resident in care homes: the optimal study protocol for realist review [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Adam L Gordon, Gordon, Adam L., Davies, Sue L., Dening, T., Bowman, C, Davies, S.L., Goodman, C., Martin, F, Gage, Heather, Martin, F. C., Iliffe, S., Gordon, A.L., Dening, Tom, Victor, CR, Gage, H., Meyer, J, Gordon, Adam L, Sue L Davies, Meyer, J., Dening, T, Gladman, J. R. F., Clive Bowman, Tom Dening, Finbarr Martin, Gladman, JRF, Gage, H, Schneider, Justine, Schneider, J, Victor, C., Heather Gage, John RF Gladman, Bowman, C., Christina Victor, Davies, SL, Victor, Christina, Gladman, John R.F., Bowman, Clive, Iliffe, S, Schneider, J., Julienne Meyer, Iliffe, Steve, Davies, Susan, Gladman, John, Goodman, Claire, Meyer, Julienne, Gordon, AL, Goodman, C, Claire Goodman, Justine Schneider, Martin, Finbarr, Steve Iliffe   +50 more
core   +2 more sources

Interprofessional team-based collaboration between designated GPs and care home staff: a qualitative study in an urban Danish setting

BMC Primary Care, 2023
Background Being a general practitioner for residents in many care homes may challenge communication with residents, relatives, and care home staff, and potentially lead to lower quality of care.
Line Due Christensen, Linda Huibers, Flemming Bro, Morten Bondo Christensen, Anna Mygind   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

In-reach specialist nursing teams for residential care homes : uptake of services, impact on care provision and cost-effectiveness [PDF]

, 2008
Background: A joint NHS-Local Authority initiative in England designed to provide a dedicated nursing and physiotherapy in-reach team (IRT) to four residential care homes has been evaluated.The IRT supported 131 residents and maintained 15 'virtual' beds
Nelson Sara, Szczepura Ala, Szczepura, Ala, Wild, Deidre, Nelson, Sara Jane, Wild Deidre, Nelson, S. (Sara), Szczepura, Ala; id_orcid, Nelson, Sarah   +8 more
core   +1 more source

Influenza and pneumococcal vaccine uptake among nursing home residents in Nottingham, England: a postal questionnaire survey

BMC Geriatrics, 2008
Background Previous studies have shown influenza vaccine uptake in UK nursing home residents to be low. Very little information exists regarding the uptake of pneumococcal vaccine in this population.
Vivancos Roberto, Copping Joanna, Shroufi Amir, Slack Richard CB   +3 more
doaj   +1 more source

Cluster randomised control trial protocol for estimating the effectiveness and cost-effectiveness of a complex intervention to increase care home staff influenza vaccination rates compared to usual practice (FLUCARE)

Trials, 2022
The care home staff influenza vaccination rate in England is significantly lower than the 75% World Health Organisation recommendation. This represents a substantial potential for resident harm.
Amrish Patel, Erika Sims, Jeanette Blacklock, Linda Birt, Veronica Bion, Allan Clark, Alys Griffiths, Cecile Guillard, Amber Hammond, Richard Holland, Andy Jones, Liz Jones, Thando Katangwe-Chigamba, Jennifer Pitcher, Po Ruby, Sion Scott, Adam P. Wagner, Saiqa Ahmed, Wasim Baqir, Luke Cook, Tony Dean, David Wright   +21 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Using pulse oximeters in care homes for residents with COVID-19 and other conditions: a rapid mixed-methods evaluation

Health and Social Care Delivery Research, 2022
Background: There are over 15,000 care homes in England, with a total of approximately 450,000 beds. Most residents are older adults, some with dementia, and other residents are people of any age with physical or learning disabilities.
Manbinder Sidhu, Ian Litchfield, Robin Miller, Naomi J Fulop, Barbara Janta, Jamie-Rae Tanner, Giulia Maistrello, Jenny Bousfield, Cecilia Vindrola-Padros, Jon Sussex   +9 more
doaj   +1 more source