Results 61 to 70 of about 3,999,178 (276)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
‘Who am I?’ How female care-leavers construct and make sense of their identity. [PDF]
, 2019 Identity formation may be more complex for those who have been in foster care in the face of childhood abuse, difficult relationships, unstable environments and multiple care contexts but this does not imply there is anything pathological about it. Given
Hassett, A., Colbridge, A.
core
Still Caring? Supporting Care Leavers in Scotland [PDF]
, 2013 This briefing paper outlines the legal, policy and practice positions for working with care leavers before going on to situate the importance of lived experiences of leaving care by young people and adult care leavers.
Hill, Louise +2 more
core +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Wohnen und Selbständigkeit. Institutionelle Unterstützung prekärer Übergänge ins Erwachsenenalter.
Schweizerische Zeitschrift für Soziale Arbeit, 2020 Verschiedene Studien aus dem Ausland zeigen, dass Jugendliche und junge Erwachsene, die aus Institutionen der Jugendhilfe oder Pflegefamilien in die Selbstständigkeit entlassen werden (Care Leavers), ein erhöhtes Risiko haben, mit Problemen wie ...
Renate Stohler, Milena Gehrig
doaj
Scottish Journal of Residential Child Care, 2021 Young people leaving the care system face significant challenges when making the transition to adulthood, with limited support from other agencies. Their outcomes are significantly poorer than those of their non-care peers. This review aims to synthesise
Philip Teer
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Life course health and mental health of care leavers after age 30: a scoping review
Scottish Journal of Residential Child CareFoster care outcome research provides critical insights into the impacts and efficacy of child welfare interventions as well as the developmental needs of those who experience placement.
Amanda Keller +3 more
doaj +1 more source