Results 41 to 50 of about 2,366 (253)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
International Journal of Adolescence and YouthThis South African qualitative study explicates the psychosocial process ‘contextualized responsiveness’, focussing on care-leavers’ responses to risks and opportunities within their social environments.
Sasambal Reuben
doaj +1 more source
Journal of Orthopaedic Surgery, 2003 Objective. T o examine if leaving special schools has a negative impact on the health care and social isolation of young adults with cerebral palsy. Methods.
SY Ng, SK Dinesh, SKH Tay, EH Lee
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2020 Care Leavers in Italy: From 'Vulnerable' Children to 'Autonomous' Adults?' (Ch11) makes appropriate use of its multiple authorship as Laura Formenti, Andrea Galimberti and Mirella Ferrari use different discursive frames to convey the problems associated with leaving care.
Formenti, Laura +2 more
openaire +2 more sources
Empowering youth in care: the case of emancipatory research with care leavers
Journal de Ciencias SocialesNew sociology of childhood has emphasized that children are capable of being reflective, of behaving purposively and are able to influence the environment where they live. This concept is also referred to as ‘children as capable agents’ meaning that they
Caterina Arciprete +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Aftercare Practitioners Facilitating the Recognition of Care-Experienced Youth in Finland
Nordisk VälfärdsforskningWhile research has highlighted the challenges care leavers face, the understanding of the specific measures taken to support them remains limited. Practitioners’ actions in embodying the welfare system by implementing relevant laws and guidelines are ...
Johanna Hedman, Riikka Korkiamäki
doaj +1 more source