Results 121 to 130 of about 4,229,194 (277)
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Children and young people in care until age 26: a must for improved outcomes
Scottish Journal of Residential Child Care, 2013 Care Leavers have the worst outcomes in our society across most social well-being indicators. This is even more shocking as they are as physically and mentally capable as any other Scot.
Duncan Dunlop
doaj +1 more source
CARE-LEAVERS’ EFFORTS TO BUILD RESILIENCE THROUGH RELATIONSHIPS OF BELONGING [PDF]
This article aims to deepen and theorise our understanding of the need for belonging among young people transitioning out of residential care. The study adopted a qualitative approach, with a sample of 31 residential care-leavers in South Africa, who ...
Reuben, Sasambal, van Breda, Adrian D
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Social Work and Society, 2014 This paper reports on the findings of a PhD research project that set out to explore how young people leaving out of home care experienced and made sense of their transition to adulthood.
John Pinkerton, Carmel Rooney
doaj +2 more sources
openLa transizione all'età adulta rappresenta per ogni adolescente un passaggio di vita decisivo e complesso, che porta con sé cambiamenti radicali nella quotidianità di chi lo affronta.
MUNARI, CLARA
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2005 One of the key skills in residential child care practice is assessment. In this edition of the journal, several writers have taken some aspect of assessment as their theme, be it risk assessment, assessment of new staff, or a tool for assessing the needs
Irene Stevens
doaj +1 more source