Results 51 to 60 of about 3,999,178 (276)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Aftercare Practitioners Facilitating the Recognition of Care-Experienced Youth in Finland

Nordisk Välfärdsforskning
While research has highlighted the challenges care leavers face, the understanding of the specific measures taken to support them remains limited. Practitioners’ actions in embodying the welfare system by implementing relevant laws and guidelines are ...
Johanna Hedman, Riikka Korkiamäki
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Current trends in the use of residential child care in Scotland [PDF]

, 2006
The survey was planned to examine how local authority residential care units were currently being used and to provide data relating to current issues in the use of residential child care. These issues were identified by Scottish Institute for Residential
Hunter, L., Milligan, I.M., Kendrick, A.
core   +4 more sources

Empowering youth in care: the case of emancipatory research with care leavers

Journal de Ciencias Sociales
New sociology of childhood has emphasized that children are capable of being reflective, of behaving purposively and are able to influence the environment where they live. This concept is also referred to as ‘children as capable agents’ meaning that they
Caterina Arciprete, Mario Biggeri, Irene Fattacciu   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

ALONE, LOST, AND UNPREPARED BY THE SYSTEM: INDIGENOUS CARE LEAVERS’ EXPERIENCES OF AGING OUT OF CHILD WELFARE CARE IN MANITOBA

International Journal of Child, Youth & Family Studies
Limited research has been carried out on Indigenous young people transitioning out of care in Canada. This article provides a coherent and meaningful account of the journey of aging out of care in the province of Manitoba, as presented by 17 Indigenous ...
Roberta L. Woodgate, Marlyn Bennett, Donna Martin, Pauline Tennent, Clayton Sandy, Shayna Plaut, Nicole Legras, Ashley Bell, Justin Lys   +8 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

New Professional Approaches for Care Leaver in Foster Care: Training “Coaching to Go!”

Lubelski Rocznik Pedagogiczny
Introduction: The number of young people with limited or non-existent social participation is growing. Characteristic is the proportion of young homeless individuals who had previous institutional contact with youth welfare.
Robert Frietsch, Dirk Holbach, Corinna Leißling   +2 more
doaj   +1 more source