Results 81 to 90 of about 3,999,178 (276)

Trajectories of care leavers according to indicators of psychosocial adjustment: A cohort analysis

open access: yesChild Protection and Practice
Background: The study of the trajectories of care leavers regarding their involvement with a series of public services and institutions contributes to identify some indicators of psychosocial adjustment and therefor make proposals of improvement in their
Carme Montserrat, Joan Llosada-Gistau
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Exploring outcomes for children who have experienced out-of-home care in Western Australia.

open access: yesInternational Journal of Population Data Science, 2018
Introduction Children who have been in out-of-home care have faced significant issues during their lives, and they are considered one of the most vulnerable groups in society.
Fernando Lima
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

What Makes a Difference? Turning Points for Young People in the Process of Leaving Placements in Public Care.

open access: yesSocial Work and Society, 2014
The purpose of this study is to examine young care leavers’ narrative accounts expressed as turning points connected to their experiences of being in care and leaving care. Telephone interviews were conducted with 65 young people, between 18 and 26 years
Ingrid Höjer, Yvonne Sjöblom
doaj   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Corporate parenting in a pandemic: Considering the delivery and receipt of support to care leavers in Wales during Covid-19. [PDF]

open access: yesChild Youth Serv Rev, 2021
Roberts L   +6 more
europepmc   +1 more source

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