Results 91 to 100 of about 2,321 (253)
Who are children in care and care leavers
, 2020 The chapter focuses on the characteristics and experiences of minors accepted in public structures and care leavers. Most of the children housed in the facilities come from problematic families, punctuated by recurrent crises. Precisely for this reason in many European countries the awareness has matured that the minors accepted in the social-welfare ...
ELISABETTA DI GIOVANNI +1 more
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Revista de Estudios SocialesBoth care leavers and non-care leavers go through a transition to adulthood marked by challenges in various aspects of their lives. However, there are significant differences between young nationals and foreign youths who have exited the protection ...
Verónica Sevillano-Monje +3 more
doaj +1 more source
Adverse and traumatic exposures, posttraumatic stress disorder, telomere length, and hair cortisol - Exploring associations in a high-risk sample of young adult residential care leavers. [PDF]
Brain Behav Immun Health, 2022 Bürgin D +9 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Children and young people in care until age 26: a must for improved outcomes
Scottish Journal of Residential Child Care, 2013 Care Leavers have the worst outcomes in our society across most social well-being indicators. This is even more shocking as they are as physically and mentally capable as any other Scot.
Duncan Dunlop
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Social Work and Society, 2014 This paper reports on the findings of a PhD research project that set out to explore how young people leaving out of home care experienced and made sense of their transition to adulthood.
John Pinkerton, Carmel Rooney
doaj +2 more sources