Results 101 to 110 of about 4,229,194 (277)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Who are children in care and care leavers
, 2020 The chapter focuses on the characteristics and experiences of minors accepted in public structures and care leavers. Most of the children housed in the facilities come from problematic families, punctuated by recurrent crises. Precisely for this reason in many European countries the awareness has matured that the minors accepted in the social-welfare ...
ELISABETTA DI GIOVANNI +1 more
openaire +1 more source
Critical Thinking and Motivation in Vocational Training and Baccalaureate: A Comparison Study of Students of Spanish Nationality, Unaccompanied Foreign Minors and Young Care Leavers. [PDF]
Int J Environ Res Public Health, 2022 Parejo-Jiménez N +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Turning Point Processes to Higher Education among Care Leavers
Social Work and Society, 2014 Children who grew up in care institutions encounter many difficulties in the years after leaving care, including challenges related to their low education achievements while they were still in care. Higher education is therefore hard and sometimes almost
Tehila Refaeli, Benjamin Strahl
doaj +2 more sources
Scottish Journal of Residential Child Care, 2020 This is a review of an overview report of a study conducted by Udayan Care in India with support from the United Nations Children's Fund (UNICEF), Tata Trusts and the five State Governments of Delhi, Gujarat, Karnataka, Maharashtra and Rajasthan.
Kenny McGhee
doaj +1 more source
Adverse and traumatic exposures, posttraumatic stress disorder, telomere length, and hair cortisol - Exploring associations in a high-risk sample of young adult residential care leavers. [PDF]
Brain Behav Immun Health, 2022 Bürgin D +9 more
europepmc +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Report di ricerca - Report della Sperimentazione Care leavers 2018 – 2023
Il Progetto Care Leavers è promosso dal Ministero del lavoro e delle politiche sociali nell’ambito del Fondo per la Lotta alla Povertà e all’Esclusione Sociale ed è realizzata in collaborazione con l’Istituto degli Innocenti.
Lucia Fagnini +15 more
core +1 more source