Results 101 to 110 of about 3,999,178 (276)

Analysis of Home Care Supports Funded by the HSE 2008–2016 [PDF]

open access: yes, 2016
This paper seeks to summarise the situation of publicly funded home care over the period 2008- 2016. Of particular interest is the overall change to the level of resources being directed to home care in the 2016 HSE Service Plan, in particular the actual
Care Alliance Ireland
core  

Report di ricerca - Report della Sperimentazione Care leavers 2018 – 2023

open access: yes
Il Progetto Care Leavers è promosso dal Ministero del lavoro e delle politiche sociali nell’ambito del Fondo per la Lotta alla Povertà e all’Esclusione Sociale ed è realizzata in collaborazione con l’Istituto degli Innocenti.
Lucia Fagnini   +15 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Factors Affecting Care Leavers in Their Transition to Adulthood: Differences Between National and Migrant Youth in Andalusia (Spain)

open access: yesRevista de Estudios Sociales
Both care leavers and non-care leavers go through a transition to adulthood marked by challenges in various aspects of their lives. However, there are significant differences between young nationals and foreign youths who have exited the protection ...
Verónica Sevillano-Monje   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Homeless Care Leavers

open access: yes, 2023
Die vorliegende Bachelorarbeit gibt einen Überblick über die Lebenswelt von Care Leaver*innen, welche von Wohnungslosigkeit bedroht oder bereits wohnungslos sind und geht auf die Handlungsmöglichkeiten der Sozialen Arbeit in der Nachbetreuung ein.
Fleischmann, Johannes
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Children and young people in care until age 26: a must for improved outcomes

open access: yesScottish Journal of Residential Child Care, 2013
Care Leavers have the worst outcomes in our society across most social well-being indicators. This is even more shocking as they are as physically and mentally capable as any other Scot.
Duncan Dunlop
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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