Results 81 to 90 of about 2,704,706 (298)
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Involvement of practice nurses and allied health professionals in the development and management of care planning processes for patients with chronic disease – A pilot study [PDF]
Medicare items were introduced in 2005 to encourage general practitioners (GPs) to involve other healthcare providers in the management of patients with chronic disease.
Kay Jones, Akuh Adaji, Peter S Schattner
doaj
Pandemic Flu Preparedness: Lessons From the Frontlines [PDF]
Outlines early lessons from the 2009 H1N1 influenza outbreak and recommendations for strengthening the U.S. core public health capacity, including vaccine stockpile and development, planning and coordination, infrastructure, and surge capacity and ...
core
Why don't we understand the public health impact of developing STI services in primary care? [PDF]
Sohal et al have attempted to evaluate the public health and economic impact of incentivized primary care services on STI diagnoses across a population.
Bailey, Angela, Cassell, Jackie
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Implementation of Family Planning and Contraception for Female Inmates in Vermont [PDF]
Background and Objective(s): Unplanned pregnancies are disproportionately high among female inmates, and incarceration provides a unique opportunity for care may be otherwise difficult to obtain, including reproductive health and family planning ...
Janowiec, Callan, FNP
core +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Background: Concerns about fragmented community mental health care have led to the development of the care programme approach in England and care and treatment planning in Wales. These systems require those people receiving mental health services to have
Alan Simpson +7 more
doaj +1 more source
Spatial accessibility and social inclusion: The impact of Portugal's last health reform [PDF]
Health policies seek to promote access to health care and should provide appropriate geographical accessibility to each demographical functional group.
Ben‐Akiva M. E. +12 more
core +1 more source

