Results 61 to 70 of about 7,414,033 (249)

MARITAL VIOLENCE CONTEXT AFTER THE MARIA DA PENHA LAW: A GROUNDED THEORY STUDY

Cogitare Enfermagem, 2019
Objective: To analyze the context of marital violence experienced by women in legal proceedings. Methodology: This is a qualitative study based on the grounded theory, conducted with 29 women in legal proceedings for marital violence and nine ...
Jordana Brock Carneiro, Nadirlene Pereira Gomes, Luana Moura Campos, Nildete Pereira Gomes, Kamylla Santos da Cunha, Ionara da Rocha Virgens, Alacoque Lorenzini Erdmann   +6 more
doaj   +1 more source

Decisions on the type and range of care services for the purposes of court proceedings

Pielęgniarstwo XXI Wieku, 2017
DECISIONS ON THE TYPE AND RANGE OF CARE SERVICES FOR THE PURPOSES OF COURT PROCEEDINGS Article 4, (1) Act of 15 July 2011 on the Professions of Nurse and Midwife specifies that the profession of a nurse encompasses providing health services.
Rafał Patryn, Irena Wrońska, Regina Lorencowicz, Cezary Łuckiewicz, Grzegorz Nowicki, Renata Domżał-Drzewicka, Renata Krzyszycha   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Discussion Paper 4 [PDF]

, 2016
It is widely understood that Family Carers are more likely to experience poor health (O’Sullivan, 2008), economic hardship (OECD, 2011), anxiety, stress, loneliness and isolation than the general population.
Care Alliance Ireland
core  

Systems for the management of respiratory disease in primary care - an international series: United Kingdom [PDF]

, 2010
INTRODUCTION: The UK National Health Service (NHS) is essentially publicly funded through general taxation. Challenges facing the NHS include the rise in prevalence of long-term conditions and financial pressures.
Allison Worth, Mark Levy, Worth, Allison, Levy, Mark L., Fletcher, Monica, Pinnock, Hilary, Aziz Sheikh, Monica Fletcher, Hilary Pinnock, Pinnock, Hilary; id_orcid, Hoskins, Gaylor, Levy, Mark, Gaylor Hoskins, Sheikh, Aziz, Levy, Mark L   +14 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Inappropriateness of health care in Canada: a systematic review protocol

Systematic Reviews, 2019
Background There is increasing recognition in Canada and globally that a substantial proportion of health care delivered is inappropriate as evidenced by (1) harmful and/or ineffective practices being overused, (2) effective clinical practices being ...
Janet E. Squires, Ian D. Graham, Doris Grinspun, John Lavis, France Légaré, Robert Bell, Stephen Bornstein, Susan E. Brien, Mark Dobrow, Megan Greenough, Carole A. Estabrooks, Michael Hillmer, Tanya Horsley, Alan Katz, Christina Krause, Wendy Levinson, Adrian Levy, Michelina Mancuso, Alies Maybee, Steve Morgan, Letitia Nadalin Penno, Andrew Neuner, Tamara Rader, Janet Roberts, Gary Teare, Joshua Tepper, Amanda Vandyk, Denise Widmeyer, Michael Wilson, Jeremy M. Grimshaw   +29 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source