The somatic care of patients with comorbid mental disorders: protocol of a mixed-methods study aiming to identify barriers to and enablers of utilization of somatic healthcare (SoKo) [PDF]
BMC Health Services Research, 2023 Background Healthcare for people with somatic and comorbid mental diseases can pose a challenge to the healthcare system. The aim of the SoKo study (the Somatic care of patients with mental Comorbidity) is to assess the current state of care and the ...
Sophie E. Groß +11 more
doaj +2 more sources
Management of Uveitis Patients on Anti-TNF Agents Who Develop Demyelinating Disease – A Case Series [PDF]
Journal of Ophthalmic Inflammation and InfectionBackground/Aims Anti-tumor necrosis factor (Anti-TNF) agents have proven beneficial for the treatment of chronic non-infectious uveitis, yet rare neurological complications and demyelinating disease can occur with their use.
Abel Hamdan +5 more
doaj +2 more sources
Unveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility [PDF]
BiomoleculesPost-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function.
Careen A. Schroeter +8 more
doaj +2 more sources
Neuro-Cells Mitigate Amyloid Plaque Formation and Behavioral Deficits in the APPswe/PS1dE9 Model of Alzheimer Disease While Also Reducing IL-6 Production in Human Monocytes [PDF]
CellsNeuroinflammation is a key feature of Alzheimer’s disease (AD), and stem cell therapies have emerged as promising candidates due to their immunomodulatory properties.
Johannes de Munter +12 more
doaj +2 more sources
Differential Cytotoxic Effects of Cell-Free Supernatants of Emerging Pathogens Escherichia albertii and Escherichia fergusonii on Four Cell Lines Reveal Vero Cells as a Putative Candidate for Cytotoxicity Analysis [PDF]
MicroorganismsEscherichia albertii and Escherichia fergusonii are recognized as emerging pathogens with zoonotic potential. Despite their increasing importance, there is a paucity of data on the cytotoxicity of these two pathogens.
Kandhan Srinivas +13 more
doaj +2 more sources
Total Thrombus-Formation System in Patients with Peripheral Artery Disease [PDF]
Clinical and Applied Thrombosis/HemostasisThe Total Thrombus-formation Analysis System (T-TAS) is an automated device using coated microchips to assess thrombus formation under flow conditions.
Christian Pfrepper MD +9 more
doaj +2 more sources
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types [PDF]
Nature CommunicationsGenome-wide spatial long-read approaches often lack single-cell resolution and yield limited read lengths. Here, we introduce spatial ISOform sequencing (Spl-ISO-Seq), which reveals exons and polyadenylation sites with near-single-cell resolution.
Careen Foord +16 more
doaj +2 more sources
Careening intracranial bullets: An existing entity? [PDF]
Surgical Neurology International, 2021 Hoz, Samer S. +4 more
openaire +3 more sources
Something on My Mind Regarding Careen Development
Zairyo To Kankyo/ Corrosion Engineering, 2016 exaly +3 more sources
Developmental shifts in computations used to detect environmental controllability.
PLoS Computational Biology, 2022 Accurate assessment of environmental controllability enables individuals to adaptively adjust their behavior-exploiting rewards when desirable outcomes are contingent upon their actions and minimizing costly deliberation when their actions are ...
Hillary A Raab +3 more
doaj +1 more source