Results 121 to 130 of about 2,894,112 (311)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Career Exploration at the Middle School Level: Barriers and Opportunities [PDF]
, 2019 In this essay, we discuss issues related to the integration of career exploration in our nation’s middle schools. We discuss the theoretical and empirical basis for career exploration at the middle school level and identify selected barriers to its ...
Godbey, Samantha, Gordon, Howard R. D.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Longitudinal study of local authority child and family social workers (wave 1) Findings from a 5 year study of local authority child and family social workers in England. [PDF]
, 2019 The longitudinal study investigates recruitment, retention and career progression in local authority child and family social work over 5 years. This is the first of 5 reports.
Coburn, S +10 more
core +3 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
, 2010 Issue Highlights: Social Media Strategies Open New Job Markets Living and Serving Abroad With The Peace Corps Alumni Profile of Martin Ceisel, Class of 2009: Rotary Ambassadorial ...
Career Center, Illinois Wesleyan University
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Hybrid nanofluids preparation, thermo-physical properties, and applications: A Review
Hybrid AdvancesNanofluids (NFs) incorporation has emerged as a pivotal advancement in the realm of technology. With the advancement in technology, new segments of NFs are introduced recently.
Bikram Singh, Shilpa Sood
doaj +1 more source
, 2009 In this issue: Alumni Profile of Brian Udovich, Class of 1998. He is now a Hollywood Film Producer! Job or Internship Searching? Time to Think Federal.The US Federal Government is still hiring.
Career Center, Illinois Wesleyan University
core +1 more source