Results 61 to 70 of about 823,985 (299)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Analisis Anteseden dan Konsekuen Pengembangan Karir Karyawan PT Pln Apj Surakarta [PDF]
, 2013 The purpose of this study was to examine the antecedent and consequent analysis of career development. This study is hypothesis testing survey method. The population in this study were all employees of PT PLN APJ Surakarta.
Cahyono, E. (Edi), Santoso, J. (Joko)
core
Hubungan Antara Dukungan Sosial Rekan Kerja Dan Komitmen Karier Pada Guru SMA Di Kota Salatiga [PDF]
, 2015 The purpose of this research is to verify the correlation between Coworker Support and Career Commitment on Teachers in Private High Schools of Department of Education, Youth and Sport. There are two scales used in this research, i.e.
Ariani, D. S. (Dwi)
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Pengaruh Kompetensi dan Pengembangan Karir terhadap Kepuasan Kerja dengan Komitmen Organisasional sebagai Variabel Mediasi (Studi Pegawai Politeknik Ilmu Pelayaran ( Pip ) Semarang) [PDF]
, 2016 An organization would expect the productivity of its employees for the achievement of organizational goals. Work productivity is seen as the ability of employees to achieve the desired results, in achieving the desired results would require a positive ...
George Wiggins (3844039) +5 more
core +4 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Role of organizational commitment in career growth and turnover intention in public sector of Oman.
PLoS ONE, 2022 IntroductionCreating a proper career program is the best way to enhance employees' organizational commitment; it motivates and retains them. This research aims to measure career growth's influence on turnover intention, mediated by employees' commitment ...
Adil Khamis Al Balushi +4 more
doaj +1 more source