Results 91 to 100 of about 699,651 (311)

Exposure to “real life” professional experiences through a shadowing scheme that matches penultimate and final year students with employers [PDF]

, 2012
This paper reports on a learning development project undertaken during 2010 – 2011. The Work-Shadowing Scheme (WSS) was primarily developed in response to feedback following the National Student Survey (NSS).
Vidal, R., Wariabharaj, M.
core  

International entrepreneurship education: postgraduate business students experiences of entrepreneurship education [PDF]

, 2012
Objectives The study aims to enhance understanding of the effectiveness of entrepreneurship education in meeting the expectations and motivations of international postgraduate students participating in UK business & management education.
David Rae, Harry Matlay, Naomi Woodier‐Harris   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Political Professionalization Beyond National Borders: An Analysis of Italian MPs in Overseas Constituencies

Politics and Governance
Among European countries, Italy is one of the relatively few cases to provide a quota of reserved parliamentary seats for non-resident citizens. Despite an increased scientific interest in the topic, the group of MPs elected in Overseas Constituencies ...
Matteo Boldrini
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Long-term tracking demonstrates effectiveness of a partnership-led training program to advance the careers of biomedical researchers from underrepresented groups.

PLoS ONE, 2019
The demographic profile of the biomedical workforce in the U.S. does not reflect the population at large, raising concerns that there will be insufficient trained researchers in the future, and the scope of research interests will not be sufficiently ...
Beti Thompson, Mary A O'Connell, Karen Peterson, Michele Shuster, Marilyn Drennan, Helena Loest, Sarah Holte, Julian A Simon, Graciela A Unguez   +8 more
doaj   +1 more source

Analysis of the Workforce and Workplace for Rheumatology, and the Research Activities of Rheumatologists Early in Their Careers [PDF]

, 2010
[Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snapshots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry.
Desjardins, Claude, Ehrenberg, Ronald G., St. Clair, E. William   +2 more
core   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Why are we here? An investigation of academic, employability and social facets of business undergraduates' motivation using Thurstone Scaling [PDF]

, 2014
In the UK employability is a key university performance measure. This reflects both the tightening graduate employment market and the demands on the sector for greater accountability.
Buglear, J
core