Results 101 to 110 of about 1,167,212 (331)

Sustainable Growth and Ethics: a Study of Business Ethics in Vietnam Between Business Students and Working Adults [PDF]

open access: yes, 2013
Sustainable growth is not only the ultimate goal of business corporations but also the primary target of local governments as well as regional and global economies. One of the cornerstones of sustainable growth is ethics.
Mujtaba, B. G. (Bahaudin)   +3 more
core   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Effect of Career Development Services on Student Career Maturity (a Study on University Student of Faculty of Adminstrative Science at Brawijaya University in Malang, East Java) [PDF]

open access: yes, 2017
This study aims to identify and explain the effect of career development services (orientation services, information services, placement and distribution services, guidance and individual counseling) simultaneously and partially on student career ...
Kawuryan, R. (Renita)   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Challenges to Developing Professional Skills in Undergraduate Chemical Engineers at a Minority Serving University [PDF]

open access: yes, 2019
Undergraduate engineering students at a minority serving institution present unique challenges for professional skill development. Students in the Chemical Process Design II and III course sequence in chemical engineering at Texas A&M University ...
Alexander, Matthew
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Career concerns and investment maturity in mutual funds [PDF]

open access: yes
An important puzzle in financial economics is why fund managers invest in short-maturity assets when they could obtain larger profits in assets with longer maturity.
Yolanda Portilla
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

The Effectiveness of Group Guidance with Modelling in Increasing The Maturity of Career Choice

open access: yesInternational Journal of Research in Counseling and Education, 2018
The maturity of the career choice direction becomes a central idea in the career development of the students. There are still many students who are less thorough in understanding career information.
Sisri Wahyuni   +2 more
doaj   +1 more source

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