Results 131 to 140 of about 25,819 (292)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Motivation and career development [PDF]
, 2009 The main objective of this diploma thesis is to outline various theories of work motivation, career growth and their practical application in sales team management within a sales organization.
Flemr, Marcel
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Andrea Vaccaro’s David and an Outline of Vaccaro’s Early Career
, 2017 "In 2014, at the suggestion of Ian Kennedy, Jeffrey Wilcox -- then registrar of the Museum of Art and Archaeology at the University of Missouri, Columbia -- sent me images of a powerful David with the Head of Goliath. I realized immediately that the artist of the painting was Andrea Vaccaro, a seventeenth-century Neapolitan painter, who lived from 1604
openaire +1 more source
Journal of Balkan and Black Sea StudiesThe lack of modern scientific work on John Hunyadi led us six years ago to initiate the research work on a monograph dedicated to his life and times, based on a critical re-evaluation of the sources on the topic, and the older and newer literature. In the pages below, we bring to the attention of the international academic community a synthesis of our ...
openaire +2 more sources
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Addendum to “Andrea Vaccaro’s David and an Outline of Vaccaro’s Early Career”
, 2017 Includes bibliographical ...
openaire +1 more source
The State of Knowledge on the Role and Impact of Labour Market Information: A Survey of the Canadian Evidence [PDF]
This report provides a critical assessment of recent Canadian efforts to measure and evaluate the impacts of labour market information (LMI). The purpose of this exercise is to provide a summary of the current state of knowledge on the role and impact of
Alexander Murray
core
Career Education: What we know, what we need to know [PDF]
, 2001 Two major influences are impacting on the nature of educational and career services in Australia, and indeed worldwide. First, well-documented changes in the world of work have changed our understanding of 'career ' and increased the importance
Wendy Patton
core