Results 141 to 150 of about 315,529 (311)

Association Between Caregiver Opposition to Topical Fluoride and Dental Radiographs [PDF]

open access: yes
Thesis (Master's)--University of Washington, 2025Purpose: The primary objective of this study was to examine the association between caregiver opposition to topical fluoride and opposition to dental radiographs. The secondary aim was to identify reasons
Lee, Kerry Hope O'Bannon
core  

Policy Brief: Live In Caregiver & Caregiver Programs, 2015-2017 [PDF]

open access: yes, 2018
This document contains three (3) policy briefs on the Live-In-Caregiver program. One from 2015, one from 2017, and one which covers the changes from 2015-2017.
Lima, Sarah   +2 more
core  

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao   +8 more
wiley   +1 more source

qcGEM: A Graph‐Based Molecular Representation With Quantum Chemistry Awareness

open access: yesAdvanced Science, EarlyView.
In this work, we introduce qcGEM, a quantum‐chemistry‐aware graph‐based embedding of molecules that incorporates physical priors into molecular representation learning. Through a specially designed model architecture to adequately process quantum chemistry information as well as three‐dimensional molecular geometry, qcGEM provides a compact, physics ...
Haoyu Wang   +3 more
wiley   +1 more source

Caregiver support in home care: a literature review on the role of the community nurse

open access: yes
openAbstract L’invecchiamento della popolazione e l’aumento delle cronicità hanno reso l’assistenza domiciliare un modello centrale nei sistemi sanitari, affidando un ruolo cruciale ai caregiver familiari.
BIANCHI, TANIA
core  

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu   +5 more
wiley   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

open access: yesAdvanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li   +3 more
wiley   +1 more source

"Educational Support for the Caregiver in the Management of Hypokinetic Syndrome in Post-Hospitalization: A Literature Review"

open access: yes
openBackground La sindrome ipocinetica rappresenta una condizione di grande rilevanza clinica e assistenziale, essa è ampiamente diffusa tra i pazienti anziani ospedalizzati, nei quali la prolungata inattività determina un progressivo declino ...
CIRIPAN, ANDREI
core  

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

open access: yesAdvanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang   +11 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

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