Results 281 to 290 of about 989,120 (394)

Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant

ChemBioChem, Accepted Article.
Gramicidin S (GS) is a cyclic decapeptide derived from two pentapeptides. The C‐terminal thioesterase (TE) domain of gramicidin S synthetase B (GrsB) dimerizes precursor pentapeptides and cyclizes the resulting linear decapeptide. Recently, a GS variant (GS‐SA), in which a single D‐Phe was replaced by L‐Ser(Allyl), was reported via precursor‐directed ...
Sho Konno, Tomoe Mizuguchi, Atsuko Suzuki, Miyu Tanaka, Fumihiro Ishikawa, Akihiro Taguchi, Atsuhiko Taniguchi, Genzoh Tanabe, Yoshio Hayashi   +8 more
wiley   +1 more source

Caregivers take care! A literary anthology of journey toward shared care.

, 2000
Kelly Landon
openalex   +2 more sources

Caregiver burden in Alzheimer's disease: Case studies [PDF]

, 2000
Kristin Martin‐Cook, Carolyn Trimmer, Doris Svetlik, Myron Weiner   +3 more
openalex   +1 more source

Symptom Onset in Classic Rett Syndrome: Analysis of Initial Clinical Severity Scale Entries

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We aim to assess the clinical features of Rett syndrome (RTT) at registration into the National Institutes of Health–sponsored natural history study (NHS) using the Clinical Severity Scale (CSS). Introduction The CSS was established in 2000 to assess characteristics of individuals with RTT and related disorders.
Alan K. Percy, Jeffrey L. Neul, Amitha Ananth, Timothy A. Benke, Eric D. Marsh   +4 more
wiley   +1 more source

Infection prevention and control in daycare centers-a survey of caregivers' knowledge and practices in Ogbomoso Community, Southwest Nigeria. [PDF]

Front Public Health
Ishola RO, Ajala DE, Olayanju G, Ilugbaro DO, Ajala RG, Dosumu TO, Ogunmodede EO.   +6 more
europepmc   +1 more source

Bioequivalence of a Donepezil/Memantine 10/20 mg Fixed‐Dose Combination Versus Single‐Component Tablets in Healthy Korean Males

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A fixed‐dose combination (FDC) tablet formulation of donepezil/memantine (10/20 mg) was developed to improve medication compliance in patients with Alzheimer's disease (AD). This study compared the pharmacokinetic (PK) characteristics and safety profiles of an FDC formulation (donepezil/memantine [10/20 mg]) and single components (SCs) of ...
Minkyu Choi, Byung Hak Jin, Do Hoon Keum, Kyoung Hoon Mo, Min Soo Park, Juhwan Lee, Sungjin Park, Choon Ok Kim   +7 more
wiley   +1 more source

Social determinants of health and their impact on depression in family caregivers of those with dementia: The importance of intermediary determinants. [PDF]

Alzheimers Dement
Cho H, Hwang Y.
europepmc   +1 more source

Predicting caregiver burden and depression in Alzheimer'sdisease

, 2000
Leah D. Clyburn, M. J. Stones, Thomas Hadjistavropoulos, Holly Tuokko   +3 more
openalex   +1 more source

Taste Profile and Relative Bioavailability of Tovorafenib Powder for Oral Suspension and Food Effect of the Tovorafenib Tablet in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang, Mike Preigh, Jing Wang, Eleni Venetsanakos, Yujin Wang, Elly Barry, Don Corson   +6 more
wiley   +1 more source

Caregiver-informed meta-synthesis of caregivers' experiences with tracheostomy decision-making in pediatrics. [PDF]

Front Pediatr
Ofosu D, Scott S, Kammerer E, Lecona L, Gibson K, Nitschke S, Thompson-Kai P, Chiarieri-Hirsch D, Qureshi N, Soril L, van Manen M, Castro-Codesal M.   +11 more
europepmc   +1 more source