Results 101 to 110 of about 239,134 (285)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Caring is easier when you do it Jointly

open access: yesInternational Journal of Integrated Care, 2014
Madeleine Starr
doaj   +3 more sources

Our canine carers

open access: yesSouth African Medical Journal, 2013
Our canine carers come from The South African Guide-Dogs Association for the Blind (SAGA), established in 1953 by Gladys Evans, herself blind, and her dog Sheena. Visit http://www.guidedog.org.za/website_who_we_are_content/54 to meet this lovely lady (recently deceased) and learn how South Africans had to be educated about these special animals!
openaire   +4 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Long-Term Conditions Questionnaire (LTCQ): a new tool for evaluation of integrated people-centred services in the context of multi-morbidity and complex care needs

open access: yesInternational Journal of Integrated Care, 2019
Introduction/Background: The Long-Term Conditions Questionnaire (LTCQ) was developed as a person-centred tool for measuring the cumulative impact of long-term health conditions (LTCs) and health-related services.
Caroline Potter   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Telehealth and Telecare: supporting unpaid carers in Scotland

open access: yesInternational Journal of Integrated Care, 2012
Donna Henderson, Anne Conlin
doaj   +3 more sources

Patient and Carer Understandings and Experiences of Living With Type 2 Diabetes in India

open access: yesHealth Expectations
Background The prevalence of type 2 diabetes (T2D) is rapidly increasing in India. Evidence suggests that adherence to both pharmacological and nonpharmacological treatment regimens combined with support from carers may help in the optimal management of ...
Rahul Krishna Puvvada   +6 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A normal paranoia? The emergence of distrust between parents of autistic children and public officials [PDF]

open access: yes, 2010
This paper explores the development of distrust and paranoia among parents and carers of autistic children in their interactions with public officials charged with such children’s diagnosis, education and care.
Ayios, A, Simpson, R
core  

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