Results 51 to 60 of about 239,134 (285)

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

The contribution of the voluntary sector to mental health crisis care: a mixed-methods study

Health Services and Delivery Research, 2020
Background: Weaknesses in the provision of mental health crisis support are evident and improvements that include voluntary sector provision are promoted.
Karen Newbigging, James Rees, Rebecca Ince, John Mohan, Doreen Joseph, Michael Ashman, Barbara Norden, Ceri Dare, Suzanne Bourke, Benjamin Costello   +9 more
doaj   +1 more source

Carers and breathlessness [PDF]

Current Opinion in Supportive & Palliative Care, 2017
Purpose of review Informal carers play a key role in supporting patients living with breathlessness in advanced disease, but with considerable impacts on their own well being. The purpose was to review recent advances in our understanding of the caring role in refractory breathlessness, its impacts on carers, and interventions ...
openaire   +4 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Treatment of anorexia nervosa: a multimethod investigation translating experimental neuroscience into clinical practice

Programme Grants for Applied Research, 2017
Background: Anorexia nervosa (AN) is a severe psychiatric condition and evidence on how to best treat it is limited. Objectives: This programme consists of seven integrated work packages (WPs) and aims to develop and test disseminable and cost-effective ...
Ulrike Schmidt, Helen Sharpe, Savani Bartholdy, Eva-Maria Bonin, Helen Davies, Abigail Easter, Elizabeth Goddard, Rebecca Hibbs, Jennifer House, Alexandra Keyes, Pooky Knightsmith, Antonia Koskina, Nicholas Magill, Jessica McClelland, Nadia Micali, Simone Raenker, Bethany Renwick, Charlotte Rhind, Mima Simic, Lot Sternheim, Sabine Woerwag-Mehta, Jennifer Beecham, Iain C Campbell, Ivan Eisler, Sabine Landau, Susan Ringwood, Helen Startup, Kate Tchanturia, Janet Treasure   +28 more
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Twelve principles to support caregiver engagement in health care systems and health research

Patient Experience Journal, 2019
Family and friend caregivers (i.e., unpaid carers) play a critical role in meeting the needs of people across various ages and illness circumstances. Caregiver experiences and expertise, which are currently overlooked, should be considered in practice ...
Kerry Kuluski, Kristina Kokorelias, Allie Peckham, Jodeme Goldhar, John Petrie, Carole Anne Alloway   +5 more
doaj  

Regenerative medicine: Stroke survivor and carer views and motivations towards a proposed stem cell clinical trial using placebo neurosurgery [PDF]

, 2018
Background  Few studies explore stroke survivor views and motivations towards stem cell therapy (SCT). This qualitative study explores the views and motivations of both stroke survivors and their partners/carers towards a proposed 2-arm Phase III ...
Abhyankar, Abhyankar, Abhyankar, Aked, Akinsanya, Alaszewski, Alfred, Anderson, Bekker, Bell, Bowling, Braun, Brown, Campbell, Connell, Coolbrandt, Dekkers, Dixon-Woods, Donovan, Donovan, Donovan, Donovan, Entwhistle, Exel, Gillies, Goetz, Greenwood, Guba, Guest, Illingworth, Juraskova, King, Knebly, Lidz, Liu, Lo, Luker, Madse, McCann, McDonald, Miles, Mills, Moorcraft, Paolucci, Rigby, Ritchie, Robinson, Sagi, Savitz, Secrest, Sinden, Singer, Stroke Association, Swift, Treweek, Welton, West, World Medical Association   +57 more
core   +3 more sources

Quality of life and well-being of carers of people with dementia: are there differences between working and nonworking carers? Results from the IDEAL program [PDF]

, 2020
The aim of this study was to identify the differences in quality of life (QoL) and well-being between working and nonworking dementia carers and the relative contribution of psychological characteristics, caregiving experience, and social support ...
Bech P., Doewick A., Dugan A. G., Healthways, Hillage J., Johannessen A., Masselot A., Newbronner L., NurFatihah O. A., Rattinger G. B., Schwarzer R.   +10 more
core   +1 more source