Results 231 to 240 of about 1,886,374 (304)

Rehandling-aware stowage planning for RoRo ships using exclusive subgraph modeling and affinity-based cargo ordering. [PDF]

Sci Rep
Lee CM, Lee H, Kim WS.
europepmc   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Exercise stress and tissue remodeling: advances in exosome-mediated RNA-RBP networks in musculoskeletal injury repair and functional recovery. [PDF]

Front Genet
Liu J, Chen H, Yang Y, Jia Z, Li Y, Zhong X, Jiang H, Mao Z, Zheng M.   +8 more
europepmc   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Hybrid endosomal coats contain different classes of sorting nexins. [PDF]

EMBO J
Gopaldass N, Roy Chowdhury S, Alves AC, Michaillat Mayer L, Comte-Misérez V, Mayer A.   +5 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Breaking barriers in peritoneal fibrosis: extracellular vesicles as promising diagnostic and therapeutic strategy. [PDF]

Ann Med
Zhong L, Zhang B, Li Y, Su B, Liao R.
europepmc   +1 more source

Cationic lipid-based nanoparticles for therapeutic delivery in cancer treatment: physicochemical characteristics, therapeutic cargos, and clinical potential. [PDF]

Appl Microsc
Bae CS, Ahn T.
europepmc   +1 more source

Protocols for Monitoring Unconventional Protein Secretion Using Luminescence and Trapping Approaches. [PDF]

Curr Protoc
Néel E, Denus M, Fargues W, Gal C, Enjolras C, Boulanger A, Parmentier ML, Villeneuve J.   +7 more
europepmc   +1 more source

Molecular Motors Orchestrate Pause-and-Run Dynamics to Facilitate Intracellular Transport. [PDF]

Biomolecules
Shen Y, Ori-McKenney KM.
europepmc   +1 more source