FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates [PDF]
, 2019 The autophagy cargo receptor p62 facilitates the condensation of misfolded, ubiquitin-positive proteins and their degradation by autophagy, but the molecular mechanism of p62 signaling to the core autophagy machinery is unclear.
Abert, Christine +9 more
core +1 more source
Recent advances in extracellular vesicles for therapeutic cargo delivery
Experimental and Molecular MedicineExosomes, which are nanosized vesicles secreted by cells, are attracting increasing interest in the field of biomedical research due to their unique properties, including biocompatibility, cargo loading capacity, and deep tissue penetration.
Hyo In Kim +5 more
semanticscholar +1 more source
Institutional and organizational features of cross-border cargo traffic in the post-soviet space integration terms. Part I [PDF]
, 2015 The article covers the technical, technological, institutional, and organizational barriers of cross-border transportation of cargo. The study uses an institutional approach as a methodological alternative to other approaches.
Ionicheva, V. N. +3 more
core +3 more sources
Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
Experimental and Molecular MedicineExtracellular vesicles (EVs), including exosomes, are increasingly recognized as potent mediators of intercellular communication due to their capacity to transport a diverse array of bioactive molecules.
Yu Jin Lee +2 more
semanticscholar +1 more source
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Molecules and Cells, 2019 Protein silencing represents an essential tool in biomedical research. Targeted protein degradation (TPD) strategies exemplified by PROTACs are rapidly emerging as modalities in drug discovery.
Daiki Takahashi +8 more
semanticscholar +1 more source
European Transport Research Review, 2021 Background The paper presents a simulation model for freight. In the paper, this model is applied to understand the impacts of electric vans and cargo bikes for the last-mile delivery of parcels.
C. Llorca, R. Moeckel
semanticscholar +1 more source
Transport of organelles by elastically coupled motor proteins
, 2016 Motor-driven cargo transport is a complex phenomenon where multiple motor proteins attached on to a cargo engage in pulling activity, often leading to tug-of-war, displaying bidirectional motion. However, most mathematical and computational models ignore
Bhat, Deepak, Gopalakrishnan, Manoj
core +1 more source
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Nature, 2014 Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered to lysosomes for degradation, is critical in diseases such as cancer and neurodegeneration.
J. Mancias +4 more
semanticscholar +1 more source
Analysis of the air cargo transport network using a complex network theory perspective
Transportation Research Part E: Logistics and Transportation Review, 2020 In this paper, we present a complex network analysis of the air transport network using the air cargo, instead of the passenger, perspective. To the best of our knowledge, this is the first work where a global cargo network comprising passenger airlines,
A. Bombelli, B. Santos, L. Tavasszy
semanticscholar +1 more source
Criteria for Selection and Evaluation of Rolling Stock of Motor Transport Enterprises
Nauka ta progres transportu, 2021 Purpose. The basic aim of the work is to analyze and substantiate the criteria for selection and evaluation of rolling stock – trucks of motor transport enterprises, based on scientific research on this issue. Methodology.
V. O Khavruk, O. O Parkhomenko
doaj +1 more source