Results 41 to 50 of about 1,869,145 (286)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Resolution of the time dependent Pn equations by a Godunov type scheme having the diffusion limit. Part 1 : The case of the time dependent P1 equations [PDF]

open access: yes, 2008
We consider the P1 model to approximate the time dependent transport equation in one dimension of space. In a diffusive regime, the solution of this system is solution of a diffusion equation.
Cargo, Patricia, Samba, Gerald
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A Test of Endogenous Trade Bloc Formation Theory on EU Data

open access: yesEast Asian Economic Review, 2007
This paper empirically confronts one explanation of spreading regionalism with the European experience. The domino theory asserts that forming a preferential trade area, or deepening an existing one, produces trade diversion that generates new political ...
Richard Edward Baldwin   +1 more
doaj   +1 more source

The impact of transformational leadership to job perfomance through self - efficacy and creativity of salesperson (Case of logistics industry in Ho Chi Minh City)

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2021
This study aim to test the impact of the transformational leadership on performance through the self – efficacy and creativity of logistics salespersons in Ho Chi Minh City. From there, the author proposes administrative implications to improve the staff’
Vũ Việt Hằng, Phan Thị Trà My
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research of remotely piloted vehicles for cargo transportation

open access: yesAviation, 2016
Remotely piloted vehicles (RPV) are used in various fields. The article analyses RPV usage for aerial cargo transportation. The first part is an overview of RPVs used across the world as cargo transportation, their examples and prototypes, as well as the
Ugnius Ragauskas   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

SOME ASPECTS OF AVIATION SERVICE MARKET

open access: yesНаучный вестник МГТУ ГА, 2018
The present day globalization in economy is closely connected with the development of air transport-one of the fastest growing sectors of economy, which provides long-distance transport, primarily to passengers.
A. V. Parkhimovich
doaj   +1 more source

An Optimization Model for Transport-Storage Logistics "An Applied Study" [PDF]

open access: yesMaǧallaẗ Al-Buḥūṯ Al-Mālīyyaẗ wa Al-Tiğāriyyaẗ, 2017
This study is concerned with improving the integrated logistic problem of transport-storage in economic institutions. It provides general proposals to support designers in constructing models and developing computer software to generate optimal logistic ...
Mohamed Mohamed Mohamed Faragallah
doaj   +1 more source

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