Results 41 to 50 of about 293,592 (310)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The impact of sea-air mode on air cargo transport [PDF]

open access: yes, 1997
The following research looks into the concept of sea-air intermodality, a combination of two or more modes of transport for the carriage of goods from origin to destination.
Al-Hajri, G.M., Al-Hajri, Ghanem Mohamed
core  

Ddigital logistics - efficient mechanism of development of transport systems

open access: yesУченые записки Российской академии предпринимательства, 2021
Modern digital technologies have turned the transportation system over and have opened new horizons in development. The formation of «digital transport and logistics» should be based on the existing frame of the transport system, but at the same time ...
E. V. Komarova, A. V. Vlasov
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Cargo-Compatible Encapsulation in Virus-Based Nanoparticles

open access: yes, 2019
Molecule encapsulation in virus-based nanoparticles (VNPs) is an emerging bioinspired way to design novel functional nanostructures and devices. Here, we report a general cargo-compatible approach to encapsulate guest materials based on the apparent ...
Xian-En Zhang (9589)   +7 more
core   +1 more source

Research of remotely piloted vehicles for cargo transportation

open access: yesAviation, 2016
Remotely piloted vehicles (RPV) are used in various fields. The article analyses RPV usage for aerial cargo transportation. The first part is an overview of RPVs used across the world as cargo transportation, their examples and prototypes, as well as the
Ugnius Ragauskas   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

SOME ASPECTS OF AVIATION SERVICE MARKET

open access: yesНаучный вестник МГТУ ГА, 2018
The present day globalization in economy is closely connected with the development of air transport-one of the fastest growing sectors of economy, which provides long-distance transport, primarily to passengers.
A. V. Parkhimovich
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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