Results 41 to 50 of about 293,592 (310)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The impact of sea-air mode on air cargo transport [PDF]
The following research looks into the concept of sea-air intermodality, a combination of two or more modes of transport for the carriage of goods from origin to destination.
Al-Hajri, G.M., Al-Hajri, Ghanem Mohamed
core
Ddigital logistics - efficient mechanism of development of transport systems
Modern digital technologies have turned the transportation system over and have opened new horizons in development. The formation of «digital transport and logistics» should be based on the existing frame of the transport system, but at the same time ...
E. V. Komarova, A. V. Vlasov
doaj
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Cargo-Compatible Encapsulation in Virus-Based Nanoparticles
Molecule encapsulation in virus-based nanoparticles (VNPs) is an emerging bioinspired way to design novel functional nanostructures and devices. Here, we report a general cargo-compatible approach to encapsulate guest materials based on the apparent ...
Xian-En Zhang (9589) +7 more
core +1 more source
Research of remotely piloted vehicles for cargo transportation
Remotely piloted vehicles (RPV) are used in various fields. The article analyses RPV usage for aerial cargo transportation. The first part is an overview of RPVs used across the world as cargo transportation, their examples and prototypes, as well as the
Ugnius Ragauskas +2 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
SOME ASPECTS OF AVIATION SERVICE MARKET
The present day globalization in economy is closely connected with the development of air transport-one of the fastest growing sectors of economy, which provides long-distance transport, primarily to passengers.
A. V. Parkhimovich
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

