Results 31 to 40 of about 131,537 (302)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Recent results from zero g cargo handling studies [PDF]

open access: yes, 1971
Cargo handling, transfer, and stowage under weightlessness conditions of space ...
Beasley, G. P.
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Technical and Economic Criteria to Select Pavement Surfaces of Port Handling Plants [PDF]

open access: yes, 2019
A port is an intermodal system in which many logistics activities requiring properly constructed areas occur. The large extension of these areas poses a major problem in choosing materials with technical and economic implications.
Di Mascio, Paola   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Security Management Policies and Work Accidents

open access: yesEconomics and Culture, 2022
Research purpose. The aim of the research is to demonstrate the impacts of an absence of organizational policies and strategies in the field of work security on enterprise competitiveness.
Monteiro Nuno, Anunciação Pedro
doaj   +1 more source

First report on containers [PDF]

open access: yes, 1966
Everybody agrees that containers are a "good thing";the actual advantages of transporting cargo, and in particular, dry cargo, in containers over other forms of transport have, to our knowledge, nowhere been stated in quantitative terms.
Kay, E., Pemberton, A. W.
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Multimodal transport planing task

open access: yesLietuvos Matematikos Rinkinys, 1997
The article deals with multimodal transport algorithm minimising cargo handling delays.
Danutė Bagdonienė
doaj   +1 more source

Estimation of Shipment Size in Seaborne Iron Ore Trade [PDF]

open access: yesTransNav, 2019
Shipment size is unavailable and important in AIS-based trade volume estimates. A method of shipment size estimates based on AIS (Automatic Identification System) data and BP neural network is proposed. The ship's length, width, designed draught, current
Xinyue Zhou, Qinyou Hu
doaj   +1 more source

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