Results 91 to 100 of about 15,360 (208)

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2885-2898, August 2026.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Bio‐inspired artificial retina with receptive fields for in‐sensor multiply‐and‐accumulate operations

open access: yesInfoMat, Volume 8, Issue 8, August 2026.
We developed a bio‐inspired artificial retina in which curved artificial receptive fields composed of perovskite photoconductors perform multiply‐and‐accumulate operations through in‐sensor computing. This architecture simultaneously realized the structural efficiency of human eyes (compact single‐lens imaging system) and functional advantages of ...
Jisang Ha   +8 more
wiley   +1 more source

Supercritical Angle Fluorescence and Raman Techniques in Biophotonics

open access: yesLaser &Photonics Reviews, Volume 20, Issue 15, 7 August 2026.
Supercritical angle fluorescence (SAF) microscopy and supercritical angle Raman (SAR) spectroscopy have emerged as powerful tools in the field of biophotonics, enabling high‐resolution imaging and spectroscopy of biological specimens near interfaces. This review article provides a comprehensive overview of the principles, techniques, applications, and ...
Subir Das   +2 more
wiley   +1 more source

Shifting the paradigm: An Indigenous knowledge‐based stewardship plan to replenish boreal caribou in Athabasca Chipewyan and Mikisew Cree First Nations' homelands

open access: yesPeople and Nature, Volume 8, Issue 8, Page 2576-2597, August 2026.
Abstract Indigenous Peoples in northern Alberta, including Dené and Cree of the Athabasca Chipewyan and Mikisew Cree First Nations (ACFN and MCFN), have been using Indigenous laws and stewardship principles to care for their homelands for thousands of years. Since ACFN and MCFN signed Treaty 8 with Canada in 1899, Alberta's land management policies and
Lori Cyprien   +6 more
wiley   +1 more source

Modeling Treatment Response in Tuberculosis Early Bactericidal Activity Trials

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Culture‐based monitoring of bacterial load is slow and susceptible to missing data, contributing to the length and cost of TB clinical trials. Non‐culture‐based alternatives, like the Tuberculosis Molecular Load Bacterial Assay (TB‐MBLA), could represent a solution.
Mairi C. W. McClean   +15 more
wiley   +1 more source

Pesticidas, pericos y sindicatos en la industria bananera costarricense, 1938-1962

open access: yesRevista de Historia, 2003
Este artículo se nutre de varias fuentes acerca de las operaciones en el Pacífico costarricense de la United Fruit Company (tiene sin embargo, referencias frecuentes a otras regiones del altamente estandarizado imperio de la compañía) para así poder ...
Steve Marquart
doaj  

Technical Debt Management in Continuous Software Engineering: State of the Art and Research Agenda

open access: yesJournal of Software: Evolution and Process, Volume 38, Issue 8, August 2026.
ABSTRACT Software companies have streamlined their engineering processes, and continuous development has been key to achieving flexible, market‐driven software solutions. Continuous software engineering (CSE) emerged as an approach to iteratively develop and maintain software, integrating business strategy, development, and operations aligned with ...
Lucas Carvalho   +4 more
wiley   +1 more source

Metoprolol Population Pharmacokinetics in Older Chinese Patients With CKM Syndrome: Joint Effects of rs1065852 and CKM2S2‐BAG Score on Clearance

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
PopPK modeling and simulation workflow for metoprolol in older Chinese patients with CKM syndrome. ABSTRACT Older adults are vulnerable to adverse drug reactions due to multimorbidity, frailty and polypharmacy. In those with cardiovascular‐kidney‐metabolic (CKM) syndrome, CKM‐related multi‐organ burden may further alter drug disposition and elevate ...
Haodi Chai   +8 more
wiley   +1 more source

A Scalable Large‐Area Fabrication Strategy for Transparent Polymeric Encapsulated Metagratings

open access: yesNanophotonics, Volume 15, Issue 14, 27 July 2026.
Transparent encapsulated polymeric guided‐mode resonant metagratings are fabricated by thermal nanoimprint lithography and experimentally validated through structural and optical characterization. The scalable fabrication strategy enables selective RGB reflection and provides a practical route toward large‐area augmented reality and wavelength ...
Francesca Filograno   +8 more
wiley   +1 more source

Captación de semilla y cultivo experimental del hacha Pinna carnea Gmelin, 1791 (Bivalvia: Pinnidae) en el Parque Nacional Natural Tayrona, Caribe colombiano.

open access: yesIntropica, 2004
Con el fin de determinar la factibilidad biologica y tecnologica del cultivo del hacha Pinna carnea en la zona norte del caribe colombiano, entre septiembre de 1994 y noviembre de 1995 se realizaron experimentos de captacion de semillas sobre colectores ...
Luz Adriana Velasco, Francisco Borrero
doaj  

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