Results 181 to 190 of about 567,535 (376)

Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post‐Kala‐Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 437-446, February 2026.
Post‐kala‐azar dermal leishmaniasis (PKDL) involves a high macrophage burden in which the Leishmania parasites reside. Liposomal amphotericin B (LAmB) plays a key role in the treatment of PKDL. The mononuclear phagocyte system (MPS) is crucial in the distribution of liposomal drugs as well as the leishmaniasis pathophysiology.
Wan‐Yu Chu, Om Prakash Singh, Shyam Sundar, Dinesh Mondal, Krishna Pandey, Pradeep Das, Ignace C. Roseboom, Sheeraz Raja, Ana Torres, Eugenia Carrillo, Alwin D.R. Huitema, Fabiana Alves, Thomas P.C. Dorlo   +12 more
wiley   +1 more source

Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 457-469, February 2026.
Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization. The pharmacokinetics (PK) of monoclonal antibodies (mAbs) during pregnancy remains poorly characterized, despite active inflammatory bowel diseases (IBD) being the greatest risk factor for adverse ...
Zrinka Duvnjak, Robin Michelet, Casper Steenholdt, Ella S.K. Widigson, Cæcilie Skejø, João A. Abrantes, Wilhelm Huisinga, Mette Julsgaard, Charlotte Kloft   +8 more
wiley   +1 more source

Dengue incidence and its relationship with El Niño oceanic index, as a sensitive variable to anticipate outbreaks in the Colombian Caribbean region [PDF]

Biomedica
Salazar-Ceballos A, Álvarez-Miño L.
europepmc   +1 more source

ECOLOGIA TROFICA DE Mugil curema, M. incilis y M. liza (PISCES: MUGILIDAE) EN LA CIENAGA GRANDE DE SANTA MARTA, CARIBE COLOMBIANO. I. ANALISIS CUALITATIVO Y CUANTITATIVO

, 2016
D Osorio Dualiby
openalex   +1 more source

Clasificación de empresas ganaderas doble propósito por calidad y canales de comercialización de la leche en el Caribe colombiano

, 2020
Elvira Durán-Rojas, Alfonso Calderón, Javier Ramírez Montoya, Universidad de Córdoba, Javier Ramírez-Montoya, Universidad de Córdoba   +5 more
openalex   +2 more sources

Using artificial intelligence as a technological tool in gynecologic and obstetric health: A narrative literature review

International Journal of Gynecology &Obstetrics, Volume 172, Issue 2, Page 850-865, February 2026.
Abstract Maternal mortality remains a critical global public health issue, particularly in low‐ and middle‐income settings where failures in surveillance, early diagnosis, and clinical decision making compromise obstetric care. In this context, the present study aimed to critically review the scientific literature on the use of artificial intelligence (
Gustavo Gonçalves dos Santos
wiley   +1 more source

Determinantes del precio de los esclavos en el caribe neogranadino en el siglo XVIII

, 2019
Adolfo Meisel-Roca, Ángela Granger Serrano, Ángela Granger Serrano, Universidad del Norte, Colombia   +3 more
openalex   +2 more sources

Preclinical Modeling and Simulation to Explore the Tissue/Plasma Exposure and Pharmacodynamic Effect of Vildagliptin in Diabetes Treatment

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Vildagliptin (VDG) is a dipeptidyl‐peptidase‐4 (DPP‐4) inhibitor used for type 2 diabetes (T2DM) treatment. Viewing to improve VDG treatment, a population pharmacokinetic (popPK) model was built to describe drug plasma, free liver and muscle concentrations determined by microdialysis in healthy and diabetic animals following 50 mg/kg i.v ...
Bruna Bernar Dias, Laura Ben Olivo, Bibiana Verlindo de Araújo   +2 more
wiley   +1 more source

Retinal Degeneration and Visual Outcomes in Patients With Bardet-Biedl Syndrome: Genotypic Influences From a Caribbean Cohort. [PDF]

Cureus
Vázquez-Folch SJ, Jiménez-Berríos GA, Izquierdo N, Garcia Rodriguez O.   +3 more
europepmc   +1 more source

Corso y piratería en el Golfo-Caribe durante las guerras de independencia hispanoamericanas

, 2004
Johanna von Grafenstein
openalex   +2 more sources