Results 161 to 170 of about 57,079 (322)

Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth   +8 more
wiley   +1 more source

Arctic National Wildlife Refuge Obstacles, Benefits, Solution [PDF]

open access: yes, 2012
I began this research project with the question, “Will the Arctic National Wildlife Refuge ever be opened with the current nation-wide opposition to it”?
Hutchison, Brittany
core  

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis   +2 more
wiley   +1 more source

Deciphering the biosynthetic pathways of lichen acids

open access: yesNew Phytologist, EarlyView.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim   +11 more
wiley   +1 more source

How to Avoid Exploratory Research [PDF]

open access: yes
Studies in marketing research often start with data rather than with a theory. This exploratory or inductive approach is at odds with the more preferred scientific method where the theory precedes the data in any single research study. (See, for example,
J.S. Armstrong
core  

Preliminary Results on the Structure and Functioning of a Taiga Watershed [PDF]

open access: yes, 1981
Comprehensive research in ecosystem functioning may logically be undertaken in the conceptual and physical context of complete drainage basins (watersheds or catchments).
Lotspeich, Frederick B.   +1 more
core  

Measuring Community Adaptive and Transformative Capacity in the Arctic Context [PDF]

open access: yes, 2016
Adaptive capacity (AC) plays a prominent role in reducing community vulnerability, an essential goal for achieving sustainability. The related concept, transformative capacity (TC), describes a set of tools from the resilience paradigm for making more ...
Berman, Matthew   +2 more
core  

Ecosystem restoration and Indigenous Peoples and local communities: Learning from protected and conserved areas

open access: yesRestoration Ecology, EarlyView.
Abstract Introduction Global interest in, and funding for, ecosystem restoration is growing in the face of ongoing ecosystem degradation. The role and inclusion of Indigenous Peoples and local communities (IP&LCs) have not been given sufficient attention in ecosystem restoration. Objective The objective of this research is to apply the lessons from the
Stephanie Mansourian
wiley   +1 more source

Living in the Mycelial World

open access: yesTopics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source

“Is This Edible Anyway?” The Impact of Culture on the Evolution (and Devolution) of Mushroom Knowledge

open access: yesTopics in Cognitive Science, EarlyView.
Abstract Mushrooms are a ubiquitous and essential component in our biological environment and have been of interest to humans around the globe for millennia. Knowledge about mushrooms represents a prime example of cumulative culture, one of the key processes in human evolution.
Andrea Bender, Åge Oterhals
wiley   +1 more source

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