Results 21 to 30 of about 13,244 (270)

NmeCas9 is an intrinsically high-fidelity genome-editing platform

Genome Biology, 2018
Background The development of CRISPR genome editing has transformed biomedical research. Most applications reported thus far rely upon the Cas9 protein from Streptococcus pyogenes SF370 (SpyCas9).
Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Paul D. Donohoue, Alexander H. Settle, Alexandra M. Lied, Kyle McGovern, Chris K. Fuller, Peter Cameron, Thomas G. Fazzio, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer   +18 more
doaj   +1 more source

Ibrutinib versus allogeneic haematopoietic stem cell transplant in relapsed/refractory del(17p) chronic lymphocytic leukaemia/small lymphocytic lymphoma. [PDF]

Br J Haematol
After adjusting for confounders, the ibrutinib cohort had significantly better overall survival (adjusted hazard ratio, 0.39; 95% confidence interval, 0.23–0.68; p = 0.0008) than the allogeneic haematopoietic stem cell transplantation (alloHSCT) cohort.
Awan FT, Liu R, Huang HH, Bye M, Ahn KW, Krigsfeld G, Raz A, Wolfe H, Hamadani M.   +8 more
europepmc   +2 more sources

Integration of woodland caribou habitat management and forest management in northern Ontario - current status and issues

Rangifer, 1998
Woodland caribou {Rangifer tarandus caribou) range across northern Ontario, occurring in both the Hudson Bay Lowlands and the Boreal Forest. Woodland caribou extend south well into the merchantable forest, occurring in licensed and/or actively managed ...
Ted (E.R) Armstrong
doaj   +1 more source

Status of northern mountain caribou (Rangifer tarandus caribou) in Yukon, Canada

Rangifer, 2013
Caribou (Rangifer tarandus) are an important ecological, cultural and economic resource in Yukon, Canada. Three caribou ecotypes occur within Yukon: Grant’s (R. t. granti), northern mountain (R. t. caribou), and boreal (R. t. caribou).
Troy M. Hegel, Kyle Russell
doaj   +1 more source

‘WildLift’: An Open-Source Tool to Guide Decisions for Wildlife Conservation

Frontiers in Ecology and Evolution, 2020
A recurring challenge for resource managers and decision makers is quantifying the trade-offs associated with alternative recovery actions for threatened species.
Mariana Nagy-Reis, Melanie Dickie, Péter Sólymos, Péter Sólymos, Sophie L. Gilbert, Craig A. DeMars, Robert Serrouya, Stan Boutin, Stan Boutin   +8 more
doaj   +1 more source

Slowing down wolves to protect boreal caribou populations: a spatial simulation model of linear feature restoration

Ecosphere, 2019
In Canada, boreal caribou (Rangifer tarandus caribou) are declining in numbers, in part due to increased predation by wolves (Canis lupus). One management option to reduce wolf–caribou interactions and thus protect caribou is to remove man‐made linear ...
Matthias C. Spangenberg, Robert Serrouya, Melanie Dickie, Craig A. DeMars, Théo Michelot, Stan Boutin, Meike J. Wittmann   +6 more
doaj   +1 more source

Caribou mine

, 2022
Mine workings map.Shows a composite of the 740, 920, 1040, 1140 and 1230 levels of the Caribou mine.
Hendricks, Thomas S.
core  

Transferrin variation and evolution of Canadian barren-ground caribou

Rangifer, 1990
Blood samples were obtained from 95 barren-ground caribou (Rangifer tarandus groenlandicus) of the Beverly herd in Northwest Territories, Canada.
Knut H. Røed, D. C. Thomas
doaj   +1 more source

Use of island and mainland shorelines by woodland caribou during the nursery period in two northern Ontario parks

Rangifer, 2011
Predation is considered a primary limiting factor of woodland caribou (Rangifer tarandus caribou) populations across North America. Caribou are especially vulnerable to predation during their first few weeks of life and have evolved space-use strategies ...
Natasha L. Carr, Arthur R. Rodgers, Steven R. Kingston, Douglas J. Lowman   +3 more
doaj   +1 more source

Woodland caribou (Rangifer tarandus) avoid wellsite activity during winter

Global Ecology and Conservation, 2021
Woodland caribou (Rangifer tarandus) are threatened in Alberta in part due to the development of oil and gas resources. To inform best management practices for caribou, we assessed how proximity to wellsites influenced caribou habitat selection, and ...
Doug MacNearney, Barry Nobert, Laura Finnegan   +2 more
doaj   +1 more source