Results 21 to 30 of about 51,337 (268)

NmeCas9 is an intrinsically high-fidelity genome-editing platform

open access: yesGenome Biology, 2018
Background The development of CRISPR genome editing has transformed biomedical research. Most applications reported thus far rely upon the Cas9 protein from Streptococcus pyogenes SF370 (SpyCas9).
Nadia Amrani   +18 more
doaj   +1 more source

Slowing down wolves to protect boreal caribou populations: a spatial simulation model of linear feature restoration

open access: yesEcosphere, 2019
In Canada, boreal caribou (Rangifer tarandus caribou) are declining in numbers, in part due to increased predation by wolves (Canis lupus). One management option to reduce wolf–caribou interactions and thus protect caribou is to remove man‐made linear ...
Matthias C. Spangenberg   +6 more
doaj   +1 more source

Woodland caribou (Rangifer tarandus) avoid wellsite activity during winter

open access: yesGlobal Ecology and Conservation, 2021
Woodland caribou (Rangifer tarandus) are threatened in Alberta in part due to the development of oil and gas resources. To inform best management practices for caribou, we assessed how proximity to wellsites influenced caribou habitat selection, and ...
Doug MacNearney   +2 more
doaj   +1 more source

Transferrin variation and evolution of Canadian barren-ground caribou

open access: yesRangifer, 1990
Blood samples were obtained from 95 barren-ground caribou (Rangifer tarandus groenlandicus) of the Beverly herd in Northwest Territories, Canada.
Knut H. Røed, D. C. Thomas
doaj   +1 more source

Stable carbon, nitrogen and sulphur isotope analysis of permafrost preserved human hair from rescue excavations (2009, 2010) at the precontact site of Nunalleq, Alaska [PDF]

open access: yes, 2018
Acknowledgments This work was funded by an Arts and Humanities Research Council (AH/K006029/1) grant awarded to Rick Knecht, Kate Britton and Charlotta Hillerdal (Aberdeen); an AHRC-LabEx award (AH/N504543/1) to KB, RK, Keith Dobney (Liverpool) and ...
Britton, Kate   +5 more
core   +1 more source

Ecosystem management and the conservation of caribou habitat in British Columbia

open access: yesRangifer, 1998
Woodland caribou (Rangifer tarandus caribou) in British Columbia inhabit a wide variety of forest ecosystems. Numerous research projects have provided information that has been used to develop caribou habitat management recommendations for different ...
Dale R. Seip
doaj   +1 more source

Use of island and mainland shorelines by woodland caribou during the nursery period in two northern Ontario parks

open access: yesRangifer, 2011
Predation is considered a primary limiting factor of woodland caribou (Rangifer tarandus caribou) populations across North America. Caribou are especially vulnerable to predation during their first few weeks of life and have evolved space-use strategies ...
Natasha L. Carr   +3 more
doaj   +1 more source

Occasional Publications on Northern Life, No. 04 [PDF]

open access: yes, 1983
The need to exchange information on research in reindeer and caribou diseases became apparent to investigators attending the Second International Reindeer/Caribou Symposium in Roros, Norway, in 1979.
Dieterich, Robert A., Morton, Jamie K.
core  

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Potential impact of restricted caribou (Rangifer tarandus) consumption on anemia prevalence among Inuit adults in northern Canada

open access: yesBMC Nutrition, 2019
Background Caribou (Rangifer tarandus) is the top dietary source of iron and several micronutrients necessary for red blood cell production (erythropoiesis) in the contemporary diet of Inuit adults across Canada.
Tiff-Annie Kenny   +5 more
doaj   +1 more source

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