Results 31 to 40 of about 165,148 (309)

Effectiveness, cost-effectiveness and cost-benefit of a single annual professional intervention for the prevention of childhood dental caries in a remote rural Indigenous community [PDF]

, 2015
Background The aim of the study is to reduce the high prevalence of tooth decay in children in a remote, rural Indigenous community in Australia, by application of a single annual dental preventive intervention.
Surani Fernando, Scuffham, Paul, Ratilal Lalloo, Yvonne Cadet-James, Tut, Ohnmar, Kularatna, Sanjeewa, Scuffham, P.A., Scuffham, Paul A, Jamieson, Lisa M., Kularatna, S., Paul A. Scuffham, Fernando, Surani, Valda Wallace, Kroon, J., Tut, O., Boase, R., Lisa M. Jamieson, Robyn Boase, Newell W. Johnson, Johnson, Newell, Wallace, V., Jeroen Kroon, Lalloo, Ratilal, Jamieson, L.M., Boase, Robyn, Johnson, Newell W., Ohnmar Tut, Cadet-James, Yvonne, Kroon, Jeroen, Sanjeewa Kularatna, Scuffham, Paul A., Lalloo, R., Johnson, N.W., Johnson, Newell W, Jamieson, Lisa M, Wallace, Valda, Fernando, S., Cadet-James, Y.   +37 more
core   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

A scoping review on the associations between early childhood caries and sustainable cities and communities using the sustainable development goal 11 framework

BMC Oral Health
Background Early childhood caries (ECC) is a multifactorial disease in which environmental factors could play a role. The purpose of this scoping review was to map the published literature that assessed the association between the Sustainable Development
Morẹ́nikẹ ́Oluwátóyìn Foláyan, Elisa Maria Rosa de Barros Coelho, Carlos Alberto Feldens, Balgis Gaffar, Jorma I Virtanen, Arthur Kemoli, Duangporn Duangthip, Ivy Guofang Sun, Ray M. Masumo, Ana Vukovic, Ola B. Al-Batayneh, Tshepiso Mfolo, Robert J Schroth, Maha El Tantawi   +13 more
doaj   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

A scoping review of the links between early childhood caries and clean water and sanitation: the Sustainable Development Goal 6

BMC Oral Health
Introduction The United Nation’s Sustainable Development Goal (SDG) 6 calls for universal access to clean water, sanitation and hygiene (WASH), which are crucial elements of health and well-being and fundamental for a life in dignity.
Yasmi O. Crystal, Yuanyuan Laura Luo, Duangporn Duangthip, Maha El Tantawi, Habib Benzian, Robert J. Schroth, Carlos Alberto Feldens, Jorma I. Virtanen, Ola B. Al-Batayneh, Aida Carolina Medina Diaz, Ana Vukovic, Verica Pavlic, Tshepiso Mfolo, Hamideh A. Daryanavard, Balgis O. Gaffar, Anas Shamala, Morẹ́nikẹ́ Oluwátóyìn Foláyan, Early Childhood Caries Advocacy Group (ECCAG)   +17 more
doaj   +1 more source

Effectiveness of mouthwashes on reducing SARS-CoV-2 viral load in oral cavity: a systematic review and meta-analysis

BMC Oral Health, 2023
Background The risk of SARS-COV-2 transmission is relatively high during dental procedures. A study was conducted to investigate the effects of mouthwashes on SARS-COV-2 viral load reduction in the oral cavity.
Tayebe Ebrahimi, Ahmad Reza Shamshiri, Masoud Alebouyeh, Simin Z. Mohebbi   +3 more
doaj   +1 more source

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source

A scoping review of early childhood caries, poverty and the first sustainable development goal

BMC Oral Health
Background Poverty is a well-known risk factor for poor health. This scoping review (ScR) mapped research linking early childhood caries (ECC) and poverty using the targets and indicators of the Sustainable Development Goal 1 (SDG1).
Maha El Tantawi, Dina Attia, Jorma I. Virtanen, Carlos Alberto Feldens, Robert J. Schroth, Ola B. Al-Batayneh, Arheiam Arheiam, Morẹ́nikẹ́ Oluwátóyìn Foláyan   +7 more
doaj   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source