Results 131 to 140 of about 407 (228)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Invierno, primavera y otoño del carlismo (1939-1976)

open access: yes, 2019
Premios: Mención especial del XV Premio Internacional Luis Hernando de Larramendi de Historia del ...

core  

La historiografía reciente sobre el segundo Carlismo (2006-2023)

open access: yes
The second Carlism is the period in the history of this movement that runs between 1868 and 1876. In this article I have analyzed more than 200 recent works on this stage, studying the profile of the researchers of Carlism, the topics covered, the ...
Caridad Salvador, Antonio   +1 more
core   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

La legitimidad española, hoy

open access: yes, 2000
El Boletín Carlista (abril). 1997 NOTAS: Nota manuscrita en la que se indica con "Mío" que el artículo pertenece a Rafael Gambra TEMA: Una oportunidad para el ...
Gambra, Rafael, 1920-2004
core  

Carlisme i reivindicació catalana a la tercera guerra

open access: yesMillars. Espai i Història, 2000
The article is inserted in the debate about the role of Carlism in the formation of Catalanism during XIXth century. According to the author, it was during the Revolutionary Sexenial (1868-1874) the first time that carlist have showed themselves in favour of returning Catalonia to the self-government, “the lost libe rties”with the decree of New Plant ...
openaire   +3 more sources

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

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