Results 141 to 150 of about 107,498 (264)

Obesity Prevalence and Associated Factors Among Users of Specialized Community Mental Health Services: An Observational Study. [PDF]

Int J Ment Health Nurs
Bruna da Cruz Diomedece T, da Silva Marinho B, Lourencetti ALS, Costa M, O'Connell M, Bellamy C, Treichel CADS.   +6 more
europepmc   +1 more source

Assessing Progression Independent of Relapse Activity in Multiple Sclerosis Using a Patient‐Reported Disability Measure and Self‐Administered Neuroperformance Outcomes

Annals of Neurology, EarlyView.
Objective The objective of this study was to investigate the ability of patient‐reported/administered outcomes to capture disability worsening and progression independent of relapse activity (PIRA) in multiple sclerosis (MS). Methods We included patients from the longitudinal multicenter MS PATHS cohort with ≥3 assessments and >6 months follow‐up. PIRA
Evy M. Reinders, Ariadna Masot‐Llima, Susana Otero‐Romero, René Carvajal, Álvaro Cobo‐Calvo, Pere Carbonell‐Mirabent, Jordina Beltran, Maria Jesús Arévalo, Helena Ariño, Georgina Arrambide, Cristina Auger, Luca Bollo, Joaquín Castilló, Manuel Comabella, Ingrid Galán, Alexis García‐Sarreón, Andrew Goodman, Carrie M. Hersh, Delon La Puma, Le H. Hua, Luciana Midaglia, Neus Mongay‐Ochoa, Ellen M. Mowry, Agustín Pappolla, Breogán Rodríguez‐Acevedo, Jordi Río, Paula Tagliani, Ángela Vidal‐Jordana, Andreu Vilaseca, Ana Zabalza, Deborah Pareto, Carlos Nos, Menno Schoonheim, Eva Strijbis, Jaume Sastre‐Garriga, Madalina Tivarus, Tjalf Ziemssen, Àlex Rovira, Xavier Montalban, Mar Tintoré, Carmen Tur   +40 more
wiley   +1 more source

SPINAL DISORDERS IN PROFESSIONAL ESPORTS ATHLETES: PROTOCOL FOR A SYSTEMATIC REVIEW. [PDF]

Acta Ortop Bras
Miachiro NY, de Menezes MD, Pontes MDS, Herrero CFPDS.   +3 more
europepmc   +1 more source

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

Annals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Dylan Reil, Manon Muntaner, Junyoung Park, Benjamin Grenier‐Boley, Marc Hulsman, Philippe Amouyel, Céline Bellenguez, Camille Charbonnier, Jean‐François Deleuze, Orio Dols‐Icardo, John Hardy, Henne Holstege, Gaël Nicolas, Simon Mead, Michael Wagner, Alfredo Ramirez, Rebecca Sims, John van Swieten, Julie Willams, Jean‐Charles Lambert, Chaitan Khosla, Yann Le Guen, Michael D Greicius   +24 more
wiley   +1 more source

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report. [PDF]

Bipolar Disord
Kupka R, Hafeman D, McCallum M, van der Markt A, Tremain H, Alda M, Almeida J, Cardoso TA, Balanzá-Martínez V, Birmaher B, Bond DJ, Brietzke E, Chendo I, Grande I, Hajek T, Hillegers M, Kauer-Sant'Anna M, Mansur R, Passos IC, Pinto AG, Post R, Tohen M, Vazquez G, Vieta E, Yatham LN, Kapczinski F, Berk M, Duffy A.   +27 more
europepmc   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Can angiotensin II affect the inflammatory response of human dental pulp cells in vitro? [PDF]

J Appl Oral Sci
Colombini-Ishikiriama BL, Dionisio TJ, Garbieri TF, Silva RAD, Oliveira SHP, Lara VS, Greene AS, Santos CFD.   +7 more
europepmc   +1 more source

Losartan-Induced Sprue-Like Enteropathy Presenting With Isolated Ileal Villous Atrophy: A Report of a Rare and Atypical Case. [PDF]

Cureus
Berrocal C, Vasquez Villada J, Galindo Orrego P, Libreros Mejia I, Delgadillo Arco DM, Suguimoto Erasso AM, Caballero Lagares M, Solano Álvarez SE, Carrascal López VA.   +8 more
europepmc   +1 more source

Implementation of a Multidisciplinary Protocol for the Safe Handling of Iodine-125 Radioactive Seeds in the Pathology Laboratory. [PDF]

Int J Breast Cancer
Rodríguez-Villena A, Schmülling UCV, Zapata IV, Rivas-Fidalgo S, Gión-Cortés M, López-Rodríguez MJ, Carretero-Barrio I, Palacios J, Pérez-Mies B.   +8 more
europepmc   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source